| Молекулярна функція | • phosphatase binding
• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity
• R-SMAD binding
• co-SMAD binding
• RNA polymerase II transcription regulatory region sequence-specific DNA binding
• transcription factor binding
• зв'язування з іоном металу
• GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding
• enzyme binding
• transforming growth factor beta receptor binding
• protein homodimerization activity
• collagen binding
• zinc ion binding
• chromatin binding
• GO:0001158 cis-regulatory region sequence-specific DNA binding
• GO:0001948, GO:0016582 protein binding
• double-stranded DNA binding
• protein kinase binding
• sequence-specific DNA binding
• DNA binding
• bHLH transcription factor binding
• ubiquitin binding
• identical protein binding
• protein heterodimerization activity
• chromatin DNA binding
• ubiquitin protein ligase binding
• beta-catenin binding
• GO:0000983 RNA polymerase II general transcription initiation factor activity
• DEAD/H-box RNA helicase binding
• mineralocorticoid receptor binding
• glucocorticoid receptor binding
• primary miRNA binding
• GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
• SMAD binding
• GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific
• GO:0001104 transcription coregulator activity
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| Біологічний процес | • somitogenesis
• skeletal system development
• ureteric bud development
• endoderm development
• regulation of transforming growth factor beta2 production
• embryonic pattern specification
• GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
• negative regulation of osteoblast differentiation
• heart looping
• positive regulation of chondrocyte differentiation
• positive regulation of alkaline phosphatase activity
• positive regulation of interleukin-1 beta production
• pericardium development
• regulation of binding
• negative regulation of wound healing
• activation of cysteine-type endopeptidase activity involved in apoptotic process
• transforming growth factor beta receptor signaling pathway
• negative regulation of inflammatory response
• positive regulation of positive chemotaxis
• negative regulation of cell population proliferation
• negative regulation of fat cell differentiation
• cell-cell junction organization
• GO:0009373 regulation of transcription, DNA-templated
• extrinsic apoptotic signaling pathway
• activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
• signal transduction involved in regulation of gene expression
• in utero embryonic development
• negative regulation of transforming growth factor beta receptor signaling pathway
• nodal signaling pathway
• GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated
• negative regulation of cell growth
• regulation of immune response
• positive regulation of transforming growth factor beta3 production
• T cell activation
• activin receptor signaling pathway
• regulation of striated muscle tissue development
• embryonic foregut morphogenesis
• positive regulation of bone mineralization
• Загоєння ран
• negative regulation of apoptotic process
• positive regulation of extracellular matrix assembly
• GO:1901227 negative regulation of transcription by RNA polymerase II
• positive regulation of epithelial to mesenchymal transition
• GO:0019049, GO:0030683 mitigation of host defenses by virus
• thyroid gland development
• developmental growth
• lens fiber cell differentiation
• гаструляція
• GO:0046730, GO:0046737, GO:0046738, GO:0046736 імунна відповідь
• osteoblast differentiation
• GO:1990744, GO:1990729 primary miRNA processing
• negative regulation of osteoblast proliferation
• osteoblast development
• embryonic cranial skeleton morphogenesis
• transdifferentiation
• paraxial mesoderm morphogenesis
• response to hypoxia
• positive regulation of cell migration
• mesoderm formation
• regulation of transforming growth factor beta receptor signaling pathway
• GO:1901313 positive regulation of gene expression
• immune system development
• positive regulation of focal adhesion assembly
• liver development
• regulation of epithelial cell proliferation
• positive regulation of stress fiber assembly
• GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
• negative regulation of mitotic cell cycle
• negative regulation of cytosolic calcium ion concentration
• canonical Wnt signaling pathway
• protein stabilization
• transcription, DNA-templated
• GO:1903363 negative regulation of protein catabolic process
• protein deubiquitination
• positive regulation of nitric oxide biosynthetic process
• negative regulation of lung blood pressure
• positive regulation of pri-miRNA transcription by RNA polymerase II
• negative regulation of cardiac muscle hypertrophy in response to stress
• cellular response to transforming growth factor beta stimulus
• cellular response to cytokine stimulus
• positive regulation of protein import into nucleus
• positive regulation of DNA-binding transcription factor activity
• SMAD protein signal transduction
• positive regulation of canonical Wnt signaling pathway
• SMAD protein complex assembly
• adrenal gland development
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