FGF10 |
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بنى متوفرة |
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بنك بيانات البروتين | Ortholog search: PDBe RCSB | قائمة رموز معرفات بنك بيانات البروتين | 1NUN | | |
معرفات |
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أسماء بديلة | FGF10, fibroblast growth factor 10 |
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معرفات خارجية | الوراثة المندلية البشرية عبر الإنترنت 602115 MGI: MGI:1099809 HomoloGene: 3284 GeneCards: 2255 |
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علم الوجود الجيني |
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وظائف جزيئية | • heparin binding • type 2 fibroblast growth factor receptor binding • growth factor activity • GO:0001948، GO:0016582 ربط بروتيني • fibroblast growth factor receptor binding • chemoattractant activity • protein tyrosine kinase activity • 1-phosphatidylinositol-3-kinase activity • phosphatidylinositol-4,5-bisphosphate 3-kinase activity |
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مكونات خلوية | • الفراغ خارج الخلية • نواة • cell surface • GO:0005578 نسيج بيني خارج الخلية • غشاء خلوي • خارج خلوي • collagen-containing extracellular matrix |
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عمليات حيوية | • bud outgrowth involved in lung branching • limb bud formation • organ growth • semicircular canal morphogenesis • embryonic pattern specification • bud elongation involved in lung branching • positive regulation of canonical Wnt signaling pathway • muscle cell fate commitment • إفراز الدموع • positive regulation of Ras protein signal transduction • positive regulation of urothelial cell proliferation • regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling • limb development • radial glial cell differentiation • female genitalia morphogenesis • mesonephros development • odontogenesis of dentin-containing tooth • prostatic bud formation • إعادة نمذجة الوعاء الدموي • regulation of saliva secretion • توليد الأوعية • establishment of mitotic spindle orientation • positive regulation of ERK1 and ERK2 cascade • embryonic digestive tract morphogenesis • تشكل العضو الحيواني • hair follicle morphogenesis • metanephros development • lung saccule development • lung epithelium development • positive regulation of Notch signaling pathway • negative regulation of cell population proliferation • branch elongation involved in salivary gland morphogenesis • branching involved in salivary gland morphogenesis • positive regulation of white fat cell proliferation • bronchiole morphogenesis • limb morphogenesis • blood vessel morphogenesis • lung development • نمو الغدة الزعترية • positive regulation of fibroblast proliferation • negative regulation of cell differentiation • ERK1 and ERK2 cascade • positive regulation of epithelial cell migration • positive regulation of mitotic cell cycle • spleen development • smooth muscle cell differentiation • GO:0060469، GO:0009371 positive regulation of transcription, DNA-templated • positive regulation of Wnt signaling pathway • Harderian gland development • protein localization to cell surface • respiratory system development • epidermis development • positive regulation of peptidyl-tyrosine phosphorylation • metanephros morphogenesis • pancreas development • mammary gland bud formation • positive chemotaxis • mesenchymal-epithelial cell signaling involved in lung development • positive regulation of hair follicle cell proliferation • lacrimal gland development • positive regulation of MAPK cascade • تمايز خلوي • positive regulation of keratinocyte proliferation • positive regulation of ATP-dependent activity • positive regulation of epithelial cell proliferation involved in wound healing • epithelial cell differentiation • organ induction • positive regulation of epithelial cell proliferation • epidermis morphogenesis • التئام الجروح • epithelial cell proliferation • regulation of activin receptor signaling pathway • positive regulation of DNA replication • انجذاب كيميائي • embryonic genitalia morphogenesis • salivary gland development • positive regulation of keratinocyte migration • response to lipopolysaccharide • نمو الغدة الدرقية • keratinocyte proliferation • semicircular canal fusion • mammary gland specification • epithelial cell migration • white fat cell differentiation • تنظيم التعبير الجيني • lung alveolus development • branching morphogenesis of an epithelial tube • embryonic digestive tract development • lung proximal/distal axis specification • fibroblast growth factor receptor signaling pathway involved in mammary gland specification • actin cytoskeleton reorganization • positive regulation of vascular endothelial growth factor receptor signaling pathway • pituitary gland development • response to estradiol • secretion by lung epithelial cell involved in lung growth • mesenchymal cell differentiation involved in lung development • lung morphogenesis • GO:1904578 response to organic cyclic compound • somatic stem cell population maintenance • tissue regeneration • otic vesicle formation • epithelial cell proliferation involved in salivary gland morphogenesis • cell-cell signaling • male genitalia morphogenesis • GO:1900404 positive regulation of DNA repair • salivary gland morphogenesis • MAPK cascade • embryonic camera-type eye development • induction of positive chemotaxis • urothelial cell proliferation • تشكل العضو الحيواني • fibroblast growth factor receptor signaling pathway • regulation of smoothened signaling pathway • determination of left/right symmetry • inner ear morphogenesis • ضبط زيادي للتكاثر الخلوي • submandibular salivary gland formation • type II pneumocyte differentiation • negative regulation of extrinsic apoptotic signaling pathway in absence of ligand • digestive tract development • regulation of epithelial cell proliferation • epithelial tube branching involved in lung morphogenesis • positive regulation of lymphocyte proliferation • GO:0003257، GO:0010735، GO:1901228، GO:1900622، GO:1904488 ضبط زيادي للنسخ انطلاقا من محفز بوليميراز الرنا الثاني • phosphatidylinositol phosphate biosynthetic process • phosphatidylinositol-3-phosphate biosynthetic process • peptidyl-tyrosine phosphorylation • regulation of signaling receptor activity • positive regulation of protein kinase B signaling • positive regulation of G1/S transition of mitotic cell cycle |
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المصادر:Amigo / QuickGO | |
تماثلات متسلسلة |
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أنواع | الإنسان | الفأر |
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أنتريه | 2255 | 14165 |
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Ensembl | ENSG00000070193 | ENSMUSG00000021732 |
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يونيبروت | | |
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RefSeq (رنا مرسال.) | | NM_004465 XM_005248264، NM_004465 |
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RefSeq (بروتين) | | XP_005248321 NP_004456، XP_005248321 |
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الموقع (UCSC | n/a | Chr 13: 118.81 – 118.93 Mb |
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بحث ببمد | [1] | [2] |
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ويكي بيانات |
اعرض/عدّل إنسان | اعرض/عدّل فأر |
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