FCER1G |
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معرفات |
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أسماء بديلة | FCER1G, FCRG, Fc fragment of IgE receptor Ig, Fc epsilon receptor Ig |
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معرفات خارجية | الوراثة المندلية البشرية عبر الإنترنت 147139 MGI: MGI:95496 HomoloGene: 3029 GeneCards: 2207 |
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علم الوجود الجيني |
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وظائف جزيئية | • IgE receptor activity • IgG binding • GO:0001948، GO:0016582 ربط بروتيني • IgE binding • transmembrane signaling receptor activity • protein homodimerization activity |
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مكونات خلوية | • مكون تكاملي للغشاء • غشاء • غشاء خلوي • Fc-epsilon receptor I complex • external side of plasma membrane • tertiary granule membrane • ficolin-1-rich granule membrane • integral component of plasma membrane • cell surface |
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عمليات حيوية | • mast cell activation • positive regulation of phagocytosis • Fc receptor mediated stimulatory signaling pathway • antigen processing and presentation of exogenous peptide antigen via MHC class II • positive regulation of interleukin-10 production • negative regulation of mast cell apoptotic process • receptor internalization • positive regulation of type IIa hypersensitivity • neutrophil activation involved in immune response • serotonin secretion by platelet • stimulatory C-type lectin receptor signaling pathway • تجلط الدم • cellular response to low-density lipoprotein particle stimulus • positive regulation of mast cell degranulation • neutrophil chemotaxis • antigen processing and presentation of exogenous peptide antigen via MHC class I • platelet activation • سبيل إشارات مستقبلات سطح الخلية • phagocytosis, engulfment • positive regulation of immune response • positive regulation of type I hypersensitivity • defense response to bacterium • immunoglobulin mediated immune response • Fc-gamma receptor signaling pathway • positive regulation of mast cell cytokine production • positive regulation of interleukin-6 production • regulation of immune response • positive regulation of tumor necrosis factor production • integrin-mediated signaling pathway • regulation of platelet activation • protein localization to plasma membrane • positive regulation of type III hypersensitivity • T cell differentiation involved in immune response • leukocyte migration • GO:0072468 توصيل الإشارة • مناعة فطرية • neutrophil degranulation • protein homooligomerization • Fc-epsilon receptor signaling pathway • osteoclast differentiation • interleukin-2 production • positive regulation of protein localization to cell surface • positive regulation of interleukin-4 production • interleukin-3-mediated signaling pathway • immune system process |
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المصادر:Amigo / QuickGO | |
تماثلات متسلسلة |
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أنواع | الإنسان | الفأر |
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أنتريه | 2207 | 14127 |
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Ensembl | ENSG00000158869 | ENSMUSG00000058715 |
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يونيبروت | | |
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RefSeq (رنا مرسال.) | | |
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RefSeq (بروتين) | | |
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الموقع (UCSC | n/a | Chr 1: 171.06 – 171.06 Mb |
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بحث ببمد | [1] | [2] |
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ويكي بيانات |
اعرض/عدّل إنسان | اعرض/عدّل فأر |
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