| EIF4G1 |
|---|
 |
| Наявні структури |
|---|
| PDB | Пошук ортологів: PDBe RCSB |
|---|
| Список кодів PDB | | 1LJ2, 1UG3, 2W97, 4AZA, 4F02 | | |
| Ідентифікатори |
|---|
| Символи | EIF4G1, EIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18, Eukaryotic translation initiation factor 4 gamma, eukaryotic translation initiation factor 4 gamma 1 |
|---|
| Зовнішні ІД | OMIM: 600495 MGI: 2384784 HomoloGene: 110725 GeneCards: EIF4G1 |
|---|
| Онтологія гена |
|---|
| Молекулярна функція | • translation initiation factor activity
• GO:0001948, GO:0016582 protein binding
• RNA binding
• mRNA binding
• ATP binding
• translation factor activity, RNA binding
• eukaryotic initiation factor 4E binding
• translation initiation factor binding
• GO:0032947 molecular adaptor activity
• cadherin binding
• identical protein binding
|
|---|
| Клітинна компонента | • гіалоплазма
• мембрана
• клітинне ядро
• цитоплазма
• Полісома
• eukaryotic translation initiation factor 4F complex
• cytosolic small ribosomal subunit
• postsynapse
|
|---|
| Біологічний процес | • nuclear-transcribed mRNA poly(A) tail shortening
• regulation of mRNA stability
• behavioral fear response
• positive regulation of neuron differentiation
• nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
• GO:0022415 viral process
• regulation of translation
• regulation of translational initiation
• cap-dependent translational initiation
• Біосинтез білків
• translational initiation
• mitochondrion organization
• positive regulation of cell population proliferation
• negative regulation of autophagy
• negative regulation of peptidyl-threonine phosphorylation
• positive regulation of cell growth
• GO:0051247, GO:0051200 positive regulation of protein metabolic process
• GO:0007571 розвойовий процес
• positive regulation of peptidyl-serine phosphorylation
• cellular macromolecule biosynthetic process
• GO:1905616 regulation of gene silencing by miRNA
• GO:1904490 regulation of cellular response to stress
• positive regulation of G1/S transition of mitotic cell cycle
• negative regulation of neuron death
• positive regulation of eukaryotic translation initiation factor 4F complex assembly
• regulation of presynapse assembly
• positive regulation of mRNA cap binding
• regulation of polysome binding
• positive regulation of cell death
• cellular response to nutrient levels
• energy homeostasis
• lung development
• response to ethanol
|
|---|
| Джерела:Amigo / QuickGO | |
| Шаблон експресії |
|---|
 |
| Більше даних |
| Ортологи |
|---|
| Види | Людина | Миша |
|---|
| Entrez | | |
|---|
| Ensembl | | |
|---|
| UniProt | | |
|---|
| RefSeq (мРНК) | NM_198244
NM_001194946
NM_001194947
NM_001291157
NM_004953
| NM_182917
NM_198241
NM_198242 |
| | NM_001005331
NM_145941
NM_001304432 |
|
|---|
| RefSeq (білок) | NP_001181875
NP_001181876
NP_001278086
NP_004944
NP_886553
| NP_937884
NP_937885
NP_937887 |
| NP_001291361
NP_666053
NP_001390389
NP_001390390
NP_001390391
| NP_001390392
NP_001390393
NP_001390394
NP_001390395
NP_001390396
NP_001390397 |
|
|---|
| Локус (UCSC) | Хр. 3: 184.31 – 184.34 Mb | Хр. 16: 20.49 – 20.51 Mb |
|---|
| PubMed search | [1] | [2] |
|---|
| Вікідані |
| Див./Ред. для людей | Див./Ред. для мишей |
|
