| PDGFB |
|---|
 |
| بنى متوفرة |
|---|
| بنك بيانات البروتين | Ortholog search: PDBe RCSB |
|---|
| قائمة رموز معرفات بنك بيانات البروتين | | 1PDG, 3MJG, 4HQU, 4HQX, 4QCI | | |
| معرفات |
|---|
| أسماء بديلة | PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis, platelet derived growth factor subunit B |
|---|
| معرفات خارجية | الوراثة المندلية البشرية عبر الإنترنت 190040 MGI: MGI:97528 HomoloGene: 74303 GeneCards: 5155 |
|---|
| علم الوجود الجيني |
|---|
| وظائف جزيئية | • protein homodimerization activity
• protein heterodimerization activity
• chemoattractant activity
• platelet-derived growth factor receptor binding
• platelet-derived growth factor binding
• superoxide-generating NADPH oxidase activator activity
• growth factor activity
• identical protein binding
• collagen binding
• GO:0001948، GO:0016582 ربط بروتيني
• phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
|---|
| مكونات خلوية | • platelet alpha granule lumen
• سيتوبلازم
• الفراغ خارج الخلية
• Golgi membrane
• basolateral plasma membrane
• cell surface
• endoplasmic reticulum lumen
• غشاء
• GO:0005578 نسيج بيني خارج الخلية
• خارج خلوي
• تجويف غولجي
• collagen-containing extracellular matrix
|
|---|
| عمليات حيوية | • activation of protein kinase B activity
• positive regulation of DNA biosynthetic process
• positive regulation of chemotaxis
• cellular response to growth factor stimulus
• positive regulation of protein tyrosine kinase activity
• peptidyl-tyrosine phosphorylation
• positive regulation of cell division
• نماء القلب
• positive regulation of glomerular filtration
• positive regulation of mitotic nuclear division
• positive regulation of MAP kinase activity
• positive regulation of metanephric mesenchymal cell migration
• positive regulation of hyaluronan biosynthetic process
• MAPK cascade
• protein phosphorylation
• positive regulation of glomerular mesangial cell proliferation
• cellular response to mycophenolic acid
• positive regulation of fibroblast proliferation
• activation of protein kinase activity
• نمو متعدد الخلايا
• positive regulation of protein autophosphorylation
• positive regulation of reactive oxygen species metabolic process
• عملية التمثيل الغذائي لأنواع الأكسجين التفاعلية
• GO:0045996 negative regulation of transcription, DNA-templated
• protein kinase C signaling
• metanephric glomerular mesangial cell development
• negative regulation of phosphatidylinositol biosynthetic process
• response to wounding
• positive regulation of phosphatidylinositol 3-kinase activity
• cell chemotaxis
• positive regulation of ERK1 and ERK2 cascade
• platelet degranulation
• ضبط زيادي للتكاثر الخلوي
• positive regulation of DNA replication
• GO:1901313 positive regulation of gene expression
• embryonic placenta development
• تأشير نظير صماوي
• monocyte chemotaxis
• positive regulation of endothelial cell proliferation
• positive regulation of phosphatidylinositol 3-kinase signaling
• positive regulation of calcium ion import
• GO:0060469، GO:0009371 positive regulation of transcription, DNA-templated
• GO:0035404 peptidyl-serine phosphorylation
• positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
• positive regulation of blood vessel endothelial cell migration
• تكون الدم
• positive regulation of cell migration
• positive regulation of peptidyl-tyrosine phosphorylation
• extracellular matrix organization
• negative regulation of protein binding
• positive regulation of MAPK cascade
• positive regulation of cyclin-dependent protein serine/threonine kinase activity
• negative regulation of platelet activation
• phosphatidylinositol phosphate biosynthetic process
• positive regulation of vascular associated smooth muscle cell migration
• positive chemotaxis
• negative regulation of vascular associated smooth muscle cell differentiation
• interleukin-18-mediated signaling pathway
• positive regulation of pri-miRNA transcription by RNA polymerase II
• negative regulation of pri-miRNA transcription by RNA polymerase II
• negative regulation of gene expression
• positive regulation of smooth muscle cell migration
• positive regulation of smooth muscle cell proliferation
• positive regulation of vascular associated smooth muscle cell dedifferentiation
• platelet-derived growth factor receptor signaling pathway
• positive regulation of vascular associated smooth muscle cell proliferation
• negative regulation of platelet-derived growth factor receptor-beta signaling pathway
• regulation of signaling receptor activity
• positive regulation of protein kinase B signaling
|
|---|
| المصادر:Amigo / QuickGO | |
| نمط التعبير عن الحمض النووي الريبوزي |
|---|
 |
| المزيد من بيانات التعبير المرجعية |
| تماثلات متسلسلة |
|---|
| أنواع | الإنسان | الفأر |
|---|
| أنتريه | 5155 | 18591 |
|---|
| Ensembl | ENSG00000100311 | ENSMUSG00000000489 |
|---|
| يونيبروت | | |
|---|
| RefSeq (رنا مرسال.) | | | NM_002608، XM_047441393، XM_047441394 NM_033016، NM_002608، XM_047441393، XM_047441394 |
| | | XM_006520592، XM_017316502 NM_011057، XM_006520592، XM_017316502 |
|
|---|
| RefSeq (بروتين) | | | NP_148937 NP_002599، NP_148937 |
| | | XP_006520655، XP_030104269، XP_030104270، XP_030104271، XP_036015133، XP_036015134 NP_035187، XP_006520655، XP_030104269، XP_030104270، XP_030104271، XP_036015133، XP_036015134 |
|
|---|
| الموقع (UCSC | n/a | Chr 15: 80 – 80.01 Mb |
|---|
| بحث ببمد | [1] | [2] |
|---|
| ويكي بيانات |
| اعرض/عدّل إنسان | اعرض/عدّل فأر |
|
بوابة طب
بوابة الكيمياء الحيوية
بوابة علم الأحياء الخلوي والجزيئي
