KIAA1012

Protein-coding gene in the species Homo sapiens
TRAPPC8
Identifiers
AliasesTRAPPC8, GSG1, HsT2706, KIAA1012, TRS85, trafficking protein particle complex 8, trafficking protein particle complex subunit 8
External IDsOMIM: 614136; MGI: 2443008; HomoloGene: 40993; GeneCards: TRAPPC8; OMA:TRAPPC8 - orthologs
Gene location (Human)
Chromosome 18 (human)
Chr.Chromosome 18 (human)[1]
Chromosome 18 (human)
Genomic location for TRAPPC8
Genomic location for TRAPPC8
Band18q12.1Start31,829,197 bp[1]
End31,953,136 bp[1]
Gene location (Mouse)
Chromosome 18 (mouse)
Chr.Chromosome 18 (mouse)[2]
Chromosome 18 (mouse)
Genomic location for TRAPPC8
Genomic location for TRAPPC8
Band18|18 A2Start20,950,280 bp[2]
End21,029,150 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • hair follicle

  • gonad

  • jejunal mucosa

  • caput epididymis

  • sperm

  • superior surface of tongue

  • renal medulla

  • cardia

  • bronchial epithelial cell

  • corpus epididymis
Top expressed in
  • superior cervical ganglion

  • otolith organ

  • utricle

  • hand

  • retinal pigment epithelium

  • skin of abdomen

  • primary oocyte

  • ciliary body

  • cumulus cell

  • transitional epithelium of urinary bladder
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • protein binding
Cellular component
  • phagophore assembly site
  • cytoplasmic vesicle
  • TRAPPIII protein complex
  • Golgi apparatus
  • cytosol
  • TRAPP complex
Biological process
  • protein localization to phagophore assembly site
  • autophagy of peroxisome
  • cytoplasm to vacuole transport by the Cvt pathway
  • autophagy of nucleus
  • endoplasmic reticulum to Golgi vesicle-mediated transport
  • vesicle-mediated transport
  • Golgi organization
  • autophagosome assembly
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

22878

75964

Ensembl

ENSG00000153339

ENSMUSG00000033382

UniProt

Q9Y2L5

n/a

RefSeq (mRNA)

NM_014939

NM_029491
NM_177038
NM_001361188
NM_001379370

RefSeq (protein)

NP_055754

n/a

Location (UCSC)Chr 18: 31.83 – 31.95 MbChr 18: 20.95 – 21.03 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein TRS85 homolog is a protein that in humans is encoded by the KIAA1012 gene.[5][6][7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000153339 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033382 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jul 1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.
  6. ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  7. ^ "Entrez Gene: KIAA1012 KIAA1012".

Further reading

  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Gavin AC, Bösche M, Krause R, et al. (2002). "Functional organization of the yeast proteome by systematic analysis of protein complexes". Nature. 415 (6868): 141–7. Bibcode:2002Natur.415..141G. doi:10.1038/415141a. PMID 11805826. S2CID 4425555.
  • Sacher M, Barrowman J, Schieltz D, et al. (2000). "Identification and characterization of five new subunits of TRAPP". Eur. J. Cell Biol. 79 (2): 71–80. doi:10.1078/S0171-9335(04)70009-6. PMID 10727015.


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