KIAA0460

Protein-coding gene in the species Homo sapiens
RPRD2
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

4FLB

Identifiers
AliasesRPRD2, KIAA0460, HSPC099, regulation of nuclear pre-mRNA domain containing 2
External IDsOMIM: 614695; MGI: 1922387; HomoloGene: 19997; GeneCards: RPRD2; OMA:RPRD2 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for RPRD2
Genomic location for RPRD2
Band1q21.2Start150,363,091 bp[1]
End150,476,566 bp[1]
Gene location (Mouse)
Chromosome 3 (mouse)
Chr.Chromosome 3 (mouse)[2]
Chromosome 3 (mouse)
Genomic location for RPRD2
Genomic location for RPRD2
Band3|3 F2.1Start95,667,653 bp[2]
End95,726,175 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • buccal mucosa cell

  • superficial temporal artery

  • oocyte

  • olfactory bulb

  • thoracic diaphragm

  • nipple

  • endothelial cell

  • renal medulla

  • cardia

  • germinal epithelium
Top expressed in
  • secondary oocyte

  • tail of embryo

  • cumulus cell

  • Rostral migratory stream

  • genital tubercle

  • atrioventricular valve

  • endocardial cushion

  • muscle of thigh

  • primitive streak

  • granulocyte
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • RNA polymerase II complex binding
Cellular component
  • RNA polymerase II, holoenzyme
  • nucleoplasm
Biological process
  • snRNA transcription by RNA polymerase II
  • mRNA 3'-end processing
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

23248

75137

Ensembl

ENSG00000163125

ENSMUSG00000028106

UniProt

Q5VT52

Q6NXI6

RefSeq (mRNA)

NM_001297673
NM_001297674
NM_015203

NM_001081293
NM_028328
NM_029180
NM_001368178
NM_001368179

NM_001368180
NM_001368181

RefSeq (protein)

NP_001284602
NP_001284603
NP_056018

NP_001074762
NP_001355107
NP_001355108
NP_001355109
NP_001355110

NP_082604

Location (UCSC)Chr 1: 150.36 – 150.48 MbChr 3: 95.67 – 95.73 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Regulation of nuclear pre-mRNA domain-containing protein 2 is a protein that in humans is encoded by the RPRD2 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163125 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028106 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Seki N, Ohira M, Nagase T, Ishikawa K, Miyajima N, Nakajima D, Nomura N, Ohara O (Feb 1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain". DNA Res. 4 (5): 345–9. doi:10.1093/dnares/4.5.345. PMID 9455484.
  6. ^ "Entrez Gene: KIAA0460 KIAA0460".

Further reading

  • Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Lehner B, Sanderson CM (2004). "A Protein Interaction Framework for Human mRNA Degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
  • Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Regulation of nuclear pre-mRNA domain-containing protein 2 (KIAA0460)



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