IST1 |
---|
![](//upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Protein_KIAA0174_PDB_3FRR.png/250px-Protein_KIAA0174_PDB_3FRR.png) |
Available structures |
---|
PDB | Ortholog search: PDBe RCSB |
---|
List of PDB id codes |
---|
3FRR, 3FRS, 4U7E, 4U7I, 4U7Y, 4WZX, 3JC1 |
|
|
Identifiers |
---|
Aliases | IST1, OLC1, KIAA0174, ESCRT-III associated factor, CHMP8, IST1 factor associated with ESCRT-III |
---|
External IDs | OMIM: 616434; MGI: 1919205; HomoloGene: 8849; GeneCards: IST1; OMA:IST1 - orthologs |
---|
Gene location (Human) |
---|
![Chromosome 16 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Ideogram_human_chromosome_16.svg/300px-Ideogram_human_chromosome_16.svg.png) | Chr. | Chromosome 16 (human)[1] |
---|
| Band | 16q22.2 | Start | 71,845,996 bp[1] |
---|
End | 71,931,199 bp[1] |
---|
|
Gene location (Mouse) |
---|
![Chromosome 8 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/1/1f/Ideogram_house_mouse_chromosome_8.svg/260px-Ideogram_house_mouse_chromosome_8.svg.png) | Chr. | Chromosome 8 (mouse)[2] |
---|
| Band | 8|8 D3 | Start | 110,397,957 bp[2] |
---|
End | 110,419,892 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - left ovary
- gastric mucosa
- rectum
- right ovary
- right uterine tube
- skin of leg
- body of uterus
- skin of abdomen
- canal of the cervix
- anterior pituitary
|
| Top expressed in | - transitional epithelium of urinary bladder
- medullary collecting duct
- vestibular sensory epithelium
- stroma of bone marrow
- superior cervical ganglion
- hair follicle
- renal corpuscle
- pyloric antrum
- gastric mucosa
- dermis
|
| More reference expression data |
|
---|
BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/f/f0/PBB_GE_KIAA0174_200851_s_at_fs.png/250px-PBB_GE_KIAA0174_200851_s_at_fs.png) | More reference expression data |
|
---|
|
Gene ontology |
---|
Molecular function | - protein domain specific binding
- protein-containing complex binding
- protein binding
- MIT domain binding
- cadherin binding
| Cellular component | - cytoplasm
- cytosol
- centrosome
- Flemming body
- microtubule organizing center
- extracellular exosome
- cytoskeleton
- cytoplasmic vesicle
- endoplasmic reticulum-Golgi intermediate compartment
- midbody
- nuclear envelope
- nucleus
- extracellular region
- azurophil granule lumen
- intracellular membrane-bounded organelle
- chromatin
| Biological process | - protein localization
- viral release from host cell
- abscission
- establishment of protein localization
- viral capsid secondary envelopment
- multivesicular body assembly
- cytokinesis
- positive regulation of collateral sprouting
- cell division
- positive regulation of proteolysis
- protein transport
- cell cycle
- ESCRT III complex disassembly
- neutrophil degranulation
- cytoskeleton-dependent cytokinesis
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | NM_014761 NM_001270975 NM_001270976 NM_001270977 NM_001270978
|
---|
NM_001270979 |
| |
---|
RefSeq (protein) | NP_001257904 NP_001257905 NP_001257906 NP_001257907 NP_001257908
|
---|
NP_055576 |
| |
---|
Location (UCSC) | Chr 16: 71.85 – 71.93 Mb | Chr 8: 110.4 – 110.42 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|