N-metilkoklaurin 3'-monooksigenaza
| N-metilkoklaurin 3'-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.71 | ||||||||
| CAS broj | 202420-37-9 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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N-metilkoklaurin 3'-monooksigenaza (EC 1.14.13.71, N-metilkoklaurinska 3'-hidroksilaza) je enzim sa sistematskim imenom (S)-N-metilkoklaurin,NADPH:kiseonik oksidoreduktaza (3'-hidroksilacija).[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (S)-N-metilkoklaurin + NADPH + H+ + O2 (S)-3'-hidroksi-N-metilkoklaurin + NADP+ + H2O
Ovaj enzim je hem-tiolatni protein (P-450) koji učestvuje u sintezi benzilizohinolinskih alkaloida kod viših biljki.
Reference
- ^ Pauli, H.H. & Kutchan, T.M. (1998). „Molecular cloning and functional heterologous expression of two alleles encoding (S)-N-methylcoclaurine 3′-hydroxylase (CYP80B1), a new methyl jasmonate-inducible cytochrome P-450-dependent mono-oxygenase of benzylisoquinoline alkaloid biosynthesis”. Plant J. 13: 793—801. PMID 9681018.
Literatura
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
- N-methylcoclaurine+3'-monooxygenase на US National Library of Medicine Medical Subject Headings (MeSH)
- п
- р
- у
- EC1 Oksidoreduktaze /spisak
- EC2 Transferaze /spisak
- EC3 Hidrolaze /spisak
- EC4 Lijaze /spisak
- EC5 Izomeraze /spisak
- EC6 Ligaze /spisak
- B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
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