Metionin adenoziltransferaza

Metionin adenoziltransferaza
Metionin adenoziltransferaza 2, tetramer, Human
Identifikatori
EC broj2.5.1.6
CAS broj9012-52-6
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum
Pretraga
PMCčlanci
PubMedčlanci
NCBIproteini

Metionin adenoziltransferaza (EC 2.5.1.6, adenozilmetionin sintetaza, ATP-metionin adenoziltransferaza, metionin S-adenoziltransferaza, metionin-aktivacioni enzim, S-adenozil-L-metionin sintetaza, S-adenozilmetionin sintaza, S-adenozilmetionin sintetaza, AdoMet sintetaza) je enzim sa sistematskim imenom ATP:L-metionin S-adenoziltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + L-metionin +H2O {\displaystyle \rightleftharpoons } fosfat + difosfat + S-adenozil-L-metionin

Reference

  1. ^ Cantoni, G.L. (1953). „S-Adenosylmethionine: A new intermediate formed enzymatically from L-methionine and adenosinetriphosphate”. J. Biol. Chem. 204: 403—416. PMID 13084611. 
  2. ^ Cantoni, G.L. & Durell, J. (1957). „Activation of methionine for transmethylation. II. The methionine-activating enzyme: studies on the mechanism of reaction”. J. Biol. Chem. 225: 1033—1048. PMID 13416303. 
  3. ^ Mudd, S.H. & Cantoni, G.L. (1958). „Activation of methionine for transmethylation. III. The methionine-activating enzyme of bakers' yeast”. J. Biol. Chem. 231: 481—492. PMID 13538985. 

Literatura

  • Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 

Spoljašnje veze

  • Methionine+adenosyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
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Teme
Tipovi
  • B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
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