Karnitin O-acetiltransferaza
| Karnitin O-acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.3.1.7 | ||||||||
| CAS broj | 9029-90-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Karnitin O-acetiltransferaza (EC 2.3.1.7, acetil-KoA-karnitinska O-acetiltransferaza, acetilkarnitinska transferaza, karnitin acetilna koenzim A transferaza, karnitinska acetilaza, karnitinska acetiltransferaza, karnitin-acetil-KoA transferaza, CATC) je enzim sa sistematskim imenom acetil-KoA:karnitin O-acetiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acetil-KoA + karnitin KoA + O-acetilkarnitin
Ovaj enzim takođe deluje na propanoil-KoA i butanoil-KoA (cf. EC 2.3.1.21, karnitin O-palmitoiltransferaza i EC 2.3.1.137, karnitin O-oktanoiltransferaza).
Reference
- ↑ Chase, J.F.A., Pearson, D.J. and Tubbs, P.K. (1965). „The preparation of crystalline carnitine acetyltransferase”. Biochim. Biophys. Acta 96: 162-165. PMID 14285260.
- ↑ Friedman, S. and Fraenkel, G. (1955). „Reversible enzymatic acetylation of carnitine”. Arch. Biochem. Biophys. 59: 491-501. PMID 13275966.
- ↑ Miyazawa, S., Ozasa, H., Furuta, S., Osumi, T. and Hashimoto, T. (1983). „Purification and properties of carnitine acetyl transferase from rat liver”. J. Biochem. (Tokyo) 93: 439-451. PMID 6404901.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH Carnitine+O-acetyltransferase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
