Izopentenil-difosfatna D-izomeraza
| Izopentenil-difosfatna D-izomeraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 5.3.3.2 | ||||||||
| CAS broj | 9033-27-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Izopentenil-difosfatna D-izomeraza (EC 5.3.3.2, izopentenilpirofosfatna Delta-izomeraza, metilbutenilpirofosfatna izomeraza, izopentenilpirofosfatna izomeraza) je enzim sa sistematskim imenom izopentenil-difosfat Delta3-Delta2-izomeraza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- izopentenil difosfat dimetilalil difosfat
Za dejstvo enzima iz Streptomyces sp. vrste CL190 su neophodni FMN i NAD(P)H kofaktori.
Reference
- ↑ Kaneda, K., Kuzuyama, T., Takagi, M., Hayakawa, Y. and Seto, H. (2001). „An unusual isopentenyl diphosphate isomerase found in the mevalonate pathway gene cluster from Streptomyces sp. strain CL190”. Proc. Natl. Acad. Sci. USA 98: 932-937. PMID 11158573.
- ↑ Bishop, J.M. (1983). „Cellular oncogenes and retroviruses”. Annu. Rev. Biochem. 52: 301-354. PMID 6351725.
- ↑ Agranoff, B.W., Eggerer, H., Henning, U. and Lynen, F. (1960). „Biosynthesis of terpenes. VII. Isopentenyl pyrophosphate isomerase”. J. Biol. Chem. 235: 326-332. PMID 13792054.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH Isopentenyl-diphosphate+Delta-isomerase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
