Gametolizin
| Gametolizin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.38 | ||||||||
| CAS broj | 97089-74-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Gametolizin (EC 3.4.24.38, autolizin, protaza razlaganja ćelijskog zida Chlamydomonas, lizin, Chlamydomonas reinhardtii metaloproteinaza, gametni litički enzim, gametni autolizin) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Razlaganje prolinom i hidroksiprolinom bogatih proteina ćelijskog zida Chlamydomonas. Takođe dolazi do razlaganja azokazeina, želatina i Leu-Trp-Met-Arg-Phe-Ala
Ovaj glikoprotein je prisutan u Chlamydomonas reinhardtii gametima.
Reference
- ↑ Jaenicke, L., Kunhe, W., Spessert, R., Wahle, U. and Waffenschmidt, S. (1987). „Cell-wall lytic enzymes (autolysins) of Chlamydomonas reinhardtii are (hydroxy)proline-specific proteases”. Eur. J. Biochem. 170: 485-491. PMID 3319620.
- ↑ Buchanan, M.J., Imam, S.H., Eskue, W.A. and Snell, W.J. (1989). „Activation of the cell wall degrading protease, lysin, during sexual signalling in Chlamydomonas: the enzyme is stored as an inactive, higher relative molecular mass precursor in the periplasm”. J. Cell. Biol. 108: 199-207. PMID 2910877.
- ↑ Matsuda, Y. (1998). „Gametolysin”. u: Barrett, A.J., Rawlings, N.D. & Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Academic Press. str. 1140-1143.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- Matsuda, Y. (1998). „Gametolysin”. u: Barrett, A.J., Rawlings, N.D. & Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Academic Press. str. 1140-1143.
Spoljašnje veze
- MeSH Gametolysin
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
