CASP8AP2 |
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Estruturas disponíveis |
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PDB | Pesquisa Human UniProt: PDBe RCSB |
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Lista de códigos id do PDB |
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2LR8 |
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Identificadores |
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Nomes alternativos | CASP8AP2 |
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IDs externos | OMIM: 606880 HomoloGene: 8066 GeneCards: CASP8AP2 |
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Ontologia genética |
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Função molecular | • peptidase activator activity involved in apoptotic process • DNA binding • death receptor binding • GO:0001106 transcription corepressor activity • SUMO polymer binding • GO:0001948, GO:0016582 ligação a proteínas plasmáticas • cysteine-type endopeptidase activator activity involved in apoptotic process
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Componente celular | • citoplasma • PML body • mitocôndria • núcleo celular • cariolinfa
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Processo biológico | • GO:0009373 regulation of transcription, DNA-templated • Fas signaling pathway • transcription, DNA-templated • cellular response to mechanical stimulus • apoptotic signaling pathway • ciclo celular • activation of cysteine-type endopeptidase activity involved in apoptotic process • extrinsic apoptotic signaling pathway via death domain receptors • GO:0072468 transdução de sinal • GO:0097285 apoptose • negative regulation of nucleic acid-templated transcription
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Sources:Amigo / QuickGO |
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Ortólogos |
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Espécie | Humano | Rato |
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Entrez | | |
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Ensembl | |
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ENSG00000118412 ENSG00000288475 |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_012115 NM_001137667 NM_001137668 |
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RefSeq (proteína) | |
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NP_001131139 NP_001131140 NP_036247 |
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Localização (UCSC) | n/a | n/a |
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Pesquisa PubMed | [1] | n/a |
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Wikidata |
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