CACNA2D1 |
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Identificadores |
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Nomes alternativos | CACNA2D1 |
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IDs externos | OMIM: 114204 HomoloGene: 579 GeneCards: CACNA2D1 |
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Doenças Geneticamente Relacionadas |
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obesidade, colite ulcerosa, fígado gorduroso[1] |
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Targeted by Drug |
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bepridil hydrochloride monohydrate[2] |
Ontologia genética |
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Função molecular | • voltage-gated calcium channel activity • metal ion binding • voltage-gated ion channel activity • calcium channel activity • voltage-gated calcium channel activity involved in cardiac muscle cell action potential • voltage-gated calcium channel activity involved in bundle of His cell action potential
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Componente celular | • Canal de cálcio dependente de voltagem • L-type voltage-gated calcium channel complex • integral component of membrane • túbulo-T • membrana plasmática • Exossoma • membrane • retículo sarcoplasmático
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Processo biológico | • regulation of ion transmembrane transport • regulation of calcium ion transport • cardiac conduction • ion transport • calcium ion transmembrane transport • calcium ion transport • GO:0015915 transport • cardiac muscle cell action potential involved in contraction • calcium ion transport into cytosol • positive regulation of high voltage-gated calcium channel activity • regulation of heart rate by cardiac conduction • calcium ion transmembrane transport via high voltage-gated calcium channel • regulation of ventricular cardiac muscle cell membrane repolarization • regulation of membrane repolarization during action potential • membrane depolarization during bundle of His cell action potential • calcium ion import across plasma membrane • regulation of calcium ion transmembrane transport via high voltage-gated calcium channel • cellular response to amyloid-beta
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Sources:Amigo / QuickGO |
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Ortólogos |
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Espécie | Humano | Rato |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_000722 NM_001302890 NM_001366867 |
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RefSeq (proteína) | |
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NP_000713 NP_001289819 NP_001353796 |
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Localização (UCSC) | n/a | n/a |
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Pesquisa PubMed | [3] | n/a |
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Wikidata |
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