Dekstrotiroksina
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| Data klinikal | |
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| Nama dagang | Choloxin |
| Nama lain | D-3,5,3',5'-tetraiodotironina |
| AHFS/Drugs.com | Multum Consumer Information |
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| Status perundangan | |
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| Pengecam | |
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| ECHA InfoCard | 100.000.094  |
| Data kimia dan fizikal | |
| Formula | C15H11I4NO4 |
| Jisim molar | 776.87 g·mol−1 |
| Model 3D (JSmol) |
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Dekstrotiroksina (nama dagang Choloxin) ialah isomer dekstroputaran tiroksina.[1] Ia dilihat dalam kajian sebagai ubat penurunan kolesterol[2] tetapi ditarik balik kerana kesan sampingan terhadap jantung. Ia meningkatkan lipase hati lalu menambah baik penggunaan trigliserida dan mengurangkan tahap lipoprotein(a) dalam Serum darah.[3]
Lihat juga
Rujukan
- ^ "Dextrothyroxine (Code C61719)". NCI Thesaurus. National Cancer Institute. 2011-11-14. Dicapai pada 2020-01-28.
- ^ Bantle JP, Hunninghake DB, Frantz ID, Kuba K, Mariash CN, Oppenheimer JH (September 1984). "Comparison of effectiveness of thyrotropin-suppressive doses of D- and L-thyroxine in treatment of hypercholesterolemia". The American Journal of Medicine. 77 (3): 475–81. doi:10.1016/0002-9343(84)90107-4. PMID 6475988.
- ^ Bommer C, Werle E, Walter-Sack I, Keller C, Gehlen F, Wanner C, dll. (January 1998). "D-thyroxine reduces lipoprotein(a) serum concentration in dialysis patients". Journal of the American Society of Nephrology. 9 (1): 90–6. PMID 9440092.
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