BCR |
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사용 가능한 구조 |
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PDB | 동원체 검색: PDBe RCSB |
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식별자 |
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다른 이름 | BCR, Bcr, 5133400C09Rik, AI561783, AI853148, mKIAA3017, ALL, BCR1, CML, D22S11, D22S662, PHL, RhoGEF and GTPase activating protein, BCR gene, BCR activator of RhoGEF and GTPase |
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외부 ID | OMIM: 151410 MGI: 88141 HomoloGene: 3192 GeneCards: BCR |
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유전자 위치 (인간) |
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| 염색체 | 22번 염색체[1] |
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| 자리 | 22q11.23 | 시작 | 23,179,704 bp[1] |
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끝 | 23,318,037 bp[1] |
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유전자 위치 (쥐) |
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| 염색체 | 10번 염색체 (쥐)[2] |
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| 자리 | 10 C1|10 38.49 cM | 시작 | 74,896,424 bp[2] |
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끝 | 75,020,753 bp[2] |
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RNA 발현 패턴 |
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Bgee | 인간 | 쥐(동원체) |
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최상위 발현 | - 기댐핵
- 꼬리핵
- 조가비핵
- 뇌하수체 전엽
- olfactory zone of nasal mucosa
- 장딴지신경
- right frontal lobe
- 전전두엽피질
- 편도체
- right lobe of thyroid gland
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| 최상위 발현 | - olfactory tubercle
- 기댐핵
- superior frontal gyrus
- 담창구
- 시각피질
- primary visual cortex
- dentate gyrus of hippocampal formation granule cell
- ventromedial nucleus
- neural layer of retina
- anterior amygdaloid area
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| 추가 참조 발현 데이터 |
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BioGPS | |
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유전자 온톨로지 |
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분자 함수 | - transferase activity
- nucleotide binding
- guanyl-nucleotide exchange factor activity
- kinase activity
- protein serine/threonine kinase activity
- 단백질 결합
- enzyme binding
- protein tyrosine kinase activity
- ATP binding
- GTPase activator activity
| 세포 성분 | - 세포질
- 세포액
- postsynaptic membrane
- 세포막
- postsynaptic density
- 세포막
- 연접
- 세포연접
- 엑소좀
- 단백질을 포함한 복합체
- Schaffer collateral - CA1 synapse
- glutamatergic synapse
- postsynaptic density, intracellular component
- intracellular anatomical structure
| 생물학적 과정 | - positive regulation of phagocytosis
- intracellular signal transduction
- neuromuscular process controlling balance
- 인산화
- regulation of cell cycle
- negative regulation of blood vessel remodeling
- 단백질 인산화
- negative regulation of cellular extravasation
- response to lipopolysaccharide
- brain development
- regulation of vascular permeability
- negative regulation of cell migration
- negative regulation of neutrophil degranulation
- inner ear morphogenesis
- protein autophosphorylation
- platelet-derived growth factor receptor signaling pathway
- regulation of Rho protein signal transduction
- regulation of small GTPase mediated signal transduction
- negative regulation of inflammatory response
- actin cytoskeleton organization
- 신호전달
- peptidyl-tyrosine phosphorylation
- renal system process
- homeostasis of number of cells
- regulation of nitrogen compound metabolic process
- definitive hemopoiesis
- negative regulation of respiratory burst
- intracellular protein transmembrane transport
- cellular response to lipopolysaccharide
- negative regulation of reactive oxygen species metabolic process
- positive regulation of GTPase activity
- modulation of chemical synaptic transmission
- small GTPase mediated signal transduction
- keratinocyte differentiation
- focal adhesion assembly
- activation of GTPase activity
| 출처: Amigo / QuickGO |
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동원체 |
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종 | 인간 | 쥐 |
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앙트레 | | |
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앙상블 | | |
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유니프롯 | | |
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RefSeq (mRNA) | | |
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RefSeq(단백질) | | |
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위치(UCSC) | Chr 22: 23.18 – 23.32 Mb | Chr 10: 74.9 – 75.02 Mb |
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PubMed 검색 | [3] | [4] |
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위키데이터 |
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