NKX2-5 |
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PDBに登録されている構造 |
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PDB | オルソログ検索: RCSB PDBe PDBj |
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識別子 |
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記号 | NKX2-5, CHNG5, CSX, CSX1, HLHS2, NKX2.5, NKX2E, NKX4-1, VSD3, NK2 homeobox 5 |
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外部ID | OMIM: 600584 MGI: 97350 HomoloGene: 3230 GeneCards: NKX2-5 |
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遺伝子の位置 (ヒト) |
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![5番染色体 (ヒト)](//upload.wikimedia.org/wikipedia/commons/thumb/6/61/Ideogram_human_chromosome_5.svg/300px-Ideogram_human_chromosome_5.svg.png) | 染色体 | 5番染色体 (ヒト)[1] |
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| バンド | データ無し | 開始点 | 173,232,109 bp[1] |
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終点 | 173,235,311 bp[1] |
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遺伝子の位置 (マウス) |
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![17番染色体 (マウス)](//upload.wikimedia.org/wikipedia/commons/thumb/1/13/Ideogram_house_mouse_chromosome_17.svg/260px-Ideogram_house_mouse_chromosome_17.svg.png) | 染色体 | 17番染色体 (マウス)[2] |
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| バンド | データ無し | 開始点 | 27,057,638 bp[2] |
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終点 | 27,063,983 bp[2] |
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遺伝子オントロジー |
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分子機能 | • DNA-binding transcription factor activity • DNA-binding transcription activator activity, RNA polymerase II-specific • 転写因子結合 • protein homodimerization activity • serum response element binding • クロマチン結合 • 血漿タンパク結合 • DNA結合 • sequence-specific DNA binding • transcription coregulator activity • protein heterodimerization activity • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding • RNA polymerase II cis-regulatory region sequence-specific DNA binding • DNA-binding transcription factor activity, RNA polymerase II-specific
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細胞の構成要素 | • 細胞質 • 細胞核 • transcription regulator complex • RNA polymerase II transcription regulator complex • 高分子複合体 • protein-DNA complex
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生物学的プロセス | • cardiac conduction system development • apoptotic process involved in heart morphogenesis • bundle of His development • regulation of transcription by RNA polymerase II • atrioventricular node cell development • outflow tract morphogenesis • embryonic heart tube development • 脈管形成 • heart looping • atrial septum morphogenesis • positive regulation of heart contraction • proepicardium development • pulmonary myocardium development • 心収縮 • ventricular cardiac muscle cell development • negative regulation of canonical Wnt signaling pathway • pharyngeal system development • atrioventricular node development • cardiac ventricle formation • regulation of transcription, DNA-templated • 心筋収縮 • regulation of cardiac muscle cell proliferation • heart trabecula formation • ventricular septum morphogenesis • cardiac muscle cell differentiation • Purkinje myocyte differentiation • 脾臓発生 • positive regulation of transcription, DNA-templated • 心臓発生 • positive regulation of neuron differentiation • positive regulation of cardioblast differentiation • septum secundum development • atrial cardiac muscle cell development • 細胞分化 • adult heart development • right ventricular cardiac muscle tissue morphogenesis • negative regulation of apoptotic process • negative regulation of transcription by RNA polymerase II • positive regulation of transcription initiation from RNA polymerase II promoter • cardiac muscle cell proliferation • BMP signaling pathway • ventricular trabecula myocardium morphogenesis • outflow tract septum morphogenesis • negative regulation of cardiac muscle cell apoptotic process • 甲状腺発生 • canonical Wnt signaling pathway • negative regulation of transcription, DNA-templated • sarcomere organization • cardiac ventricle morphogenesis • regulation of cardiac conduction • cardiac muscle tissue development • embryonic heart tube left/right pattern formation • heart morphogenesis • cardiac muscle tissue morphogenesis • 多細胞個体の発生 • positive regulation of gene expression • positive regulation of cell population proliferation • positive regulation of sodium ion transport • negative regulation of myotube differentiation • regulation of cardiac muscle contraction • ventricular cardiac myofibril assembly • atrioventricular node cell fate commitment • positive regulation of transcription by RNA polymerase II • transcription by RNA polymerase II • 造血
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出典:Amigo / QuickGO |
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オルソログ |
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種 | ヒト | マウス |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_004387 NM_001166175 NM_001166176 |
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RefSeq (タンパク質) | |
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NP_001159647 NP_001159648 NP_004378 |
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場所 (UCSC) | Chr 5: 173.23 – 173.24 Mb | Chr 5: 27.06 – 27.06 Mb |
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PubMed検索 | [3] | [4] |
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ウィキデータ |
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