CD47 |
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Structures disponibles |
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PDB | Recherche d'orthologue: PDBe RCSB |
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Identifiants PDB |
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2JJS, 2JJT, 2VSC, 4CMM, 4KJY, 5IWL |
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Identifiants |
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Aliases | CD47 |
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IDs externes | OMIM: 601028 MGI: 96617 HomoloGene: 1346 GeneCards: CD47 |
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Position du gène (Homme) |
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| Chr. | Chromosome 3 humain[1] |
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| Locus | 3q13.12 | Début | 108,043,091 bp[1] |
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Fin | 108,091,862 bp[1] |
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Position du gène (Souris) |
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| Chr. | Chromosome 16 (souris)[2] |
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| Locus | 16|16 B5 | Début | 49,620,896 bp[2] |
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Fin | 49,735,373 bp[2] |
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Expression génétique |
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Bgee | Humain | Souris (orthologue) |
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Fortement exprimé dans | - gingival epithelium
- palpebral conjunctiva
- germinal epithelium
- pleura viscéral
- right uterine tube
- pancreatic epithelial cell
- epithelium of nasopharynx
- Brodmann area 23
- tibia
- pancreatic ductal cell
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| Fortement exprimé dans | - fetal liver hematopoietic progenitor cell
- tibiofemoral joint
- sang
- medial dorsal nucleus
- gyrus cingulaire
- Corps géniculé latéral
- nerf ischiatique
- Vermis du cervelet
- gastrula
- rate
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| Plus de données d'expression de référence |
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BioGPS |
| Plus de données d'expression de référence |
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Gene Ontology |
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Fonction moléculaire | - thrombospondin receptor activity
- liaison protéique
- protein binding involved in heterotypic cell-cell adhesion
- cell-cell adhesion mediator activity
| Composant cellulaire | - integral component of membrane
- membrane plasmique
- integral component of plasma membrane
- membrane
- specific granule membrane
- tertiary granule membrane
- exosome
- surface cellulaire
| Processus biologique | - integrin-mediated signaling pathway
- positive regulation of phagocytosis
- adhésion cellulaire
- extracellular matrix organization
- positive regulation of inflammatory response
- positive regulation of T cell activation
- response to bacterium
- leukocyte migration
- positive regulation of cell population proliferation
- opsonisation
- positive regulation of cell-cell adhesion
- neutrophil degranulation
- migration cellulaire
- regulation of interferon-gamma production
- regulation of interleukin-10 production
- regulation of interleukin-12 production
- regulation of interleukin-6 production
- regulation of tumor necrosis factor production
- heterotypic cell-cell adhesion
- monocyte extravasation
- regulation of nitric oxide biosynthetic process
- positive regulation of stress fiber assembly
- cellular response to interferon-gamma
- cellular response to interleukin-1
- cellular response to interleukin-12
- cell-cell adhesion
- negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
| Sources:Amigo / QuickGO |
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Orthologues |
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Espèces | Homme | Souris |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001025079 NM_001025080 NM_001777 NM_198793 NM_001382306 |
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NM_010581 NM_001368415 NM_001368416 NM_001368417 NM_001368418 |
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RefSeq (protéine) | |
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NP_001768 NP_942088 NP_001369235 |
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NP_034711 NP_001355344 NP_001355345 NP_001355346 NP_001355347 |
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Localisation (UCSC) | Chr 3: 108.04 – 108.09 Mb | Chr 16: 49.62 – 49.74 Mb |
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Publication PubMed | [3] | [4] |
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Wikidata |
Voir/Editer Humain | Voir/Editer Souris |
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