VPS11 |
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Identifiers |
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Aliases | VPS11, END1, PEP5, RNF108, hHLD12, CORVET/HOPS core subunit, VPS11 core subunit of CORVET and HOPS complexes |
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External IDs | OMIM: 608549; MGI: 1918982; HomoloGene: 6673; GeneCards: VPS11; OMA:VPS11 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 11 (human)[1] |
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| Band | 11q23.3 | Start | 119,067,692 bp[1] |
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End | 119,081,978 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 9 (mouse)[2] |
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| Band | 9|9 A5.2 | Start | 44,259,046 bp[2] |
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End | 44,272,967 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - prefrontal cortex
- pituitary gland
- apex of heart
- right frontal lobe
- anterior pituitary
- right hemisphere of cerebellum
- right adrenal gland
- primary visual cortex
- putamen
- right adrenal cortex
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| Top expressed in | - interventricular septum
- granulocyte
- neural layer of retina
- dentate gyrus of hippocampal formation granule cell
- superior frontal gyrus
- primary visual cortex
- ankle
- muscle of thigh
- cerebellar cortex
- right kidney
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - nucleotide binding
- protein-macromolecule adaptor activity
- protein domain specific binding
- metal ion binding
- protein binding
- syntaxin binding
| Cellular component | - HOPS complex
- endosome
- late endosome
- late endosome membrane
- membrane
- endocytic vesicle
- autophagosome
- lysosomal membrane
- early endosome
- lysosome
- cytoplasmic vesicle
- clathrin-coated vesicle
| Biological process | - endosomal vesicle fusion
- regulation of protein stability
- regulation of organelle assembly
- positive regulation of protein targeting to mitochondrion
- endosome to lysosome transport
- autophagy
- positive regulation of early endosome to late endosome transport
- protein transport
- intracellular protein transport
- vesicle-mediated transport
- regulation of SNARE complex assembly
- lysosome organization
- endosome organization
- vesicle docking involved in exocytosis
- transport
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | |
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ENSG00000160695 ENSG00000280616 |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | NP_001277114 NP_068375 NP_001365147 NP_001365148 NP_001365149
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NP_001365150 |
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Location (UCSC) | Chr 11: 119.07 – 119.08 Mb | Chr 9: 44.26 – 44.27 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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