UCHL5 |
---|
|
Available structures |
---|
PDB | Ortholog search: PDBe RCSB |
---|
List of PDB id codes |
---|
3A7S, 3IHR, 3RII, 3RIS, 3TB3, 4UEL, 4UEM, 4UF5, 4UF6, 4WLP |
|
|
Identifiers |
---|
Aliases | UCHL5, CGI-70, INO80R, UCH-L5, UCH37, Ubiquitin carboxyl-terminal hydrolase L5, ubiquitin C-terminal hydrolase L5 |
---|
External IDs | OMIM: 610667; MGI: 1914848; HomoloGene: 9326; GeneCards: UCHL5; OMA:UCHL5 - orthologs |
---|
Gene location (Human) |
---|
| Chr. | Chromosome 1 (human)[1] |
---|
| Band | 1q31.2 | Start | 193,012,250 bp[1] |
---|
End | 193,060,080 bp[1] |
---|
|
Gene location (Mouse) |
---|
| Chr. | Chromosome 1 (mouse)[2] |
---|
| Band | 1 F|1 62.54 cM | Start | 143,653,010 bp[2] |
---|
End | 143,683,204 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - Achilles tendon
- islet of Langerhans
- body of pancreas
- prefrontal cortex
- muscle of thigh
- rectum
- monocyte
- gonad
- gastrocnemius muscle
- epithelium of colon
|
| Top expressed in | - morula
- embryo
- blastocyst
- yolk sac
- parotid gland
- otic placode
- tail of embryo
- medial vestibular nucleus
- deep cerebellar nuclei
- epiblast
|
| More reference expression data |
|
---|
BioGPS |
| More reference expression data |
|
---|
|
Gene ontology |
---|
Molecular function | - cysteine-type peptidase activity
- thiol-dependent deubiquitinase
- peptidase activity
- protein binding
- endopeptidase inhibitor activity
- hydrolase activity
- RNA binding
- proteasome binding
| Cellular component | - cytoplasm
- intracellular anatomical structure
- proteasome complex
- nucleus
- cytosolic proteasome complex
- nucleoplasm
- mitochondrion
- cytosol
- Ino80 complex
| Biological process | - regulation of proteasomal protein catabolic process
- DNA recombination
- regulation of transcription, DNA-templated
- lateral ventricle development
- ubiquitin-dependent protein catabolic process
- transcription, DNA-templated
- proteolysis
- cellular response to DNA damage stimulus
- forebrain morphogenesis
- DNA repair
- midbrain development
- negative regulation of endopeptidase activity
- protein deubiquitination
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | NM_001199261 NM_001199262 NM_001199263 NM_015984 NM_001350840
|
---|
NM_001350841 NM_001350842 NM_001350843 NM_001350844 NM_001350845 NM_001350846 NM_001350847 NM_001350848 NM_001350849 NM_001350850 NM_001350851 NM_001350852 |
| |
---|
RefSeq (protein) | NP_001186190 NP_001186191 NP_001186192 NP_057068 NP_001337769
|
---|
NP_001337770 NP_001337771 NP_001337772 NP_001337773 NP_001337774 NP_001337775 NP_001337776 NP_001337777 NP_001337778 NP_001337779 NP_001337780 NP_001337781 |
| |
---|
Location (UCSC) | Chr 1: 193.01 – 193.06 Mb | Chr 1: 143.65 – 143.68 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|