SUPT20H

Protein-coding gene in the species Homo sapiens
SUPT20H
Identifiers
AliasesSUPT20H, C13, C13orf19, FAM48A, P38IP, SPT20, FP757, SPT20 homolog, SAGA complex component
External IDsOMIM: 613417; MGI: 1929651; HomoloGene: 133929; GeneCards: SUPT20H; OMA:SUPT20H - orthologs
Gene location (Human)
Chromosome 13 (human)
Chr.Chromosome 13 (human)[1]
Chromosome 13 (human)
Genomic location for SUPT20H
Genomic location for SUPT20H
Band13q13.3Start37,009,312 bp[1]
End37,059,713 bp[1]
Gene location (Mouse)
Chromosome 3 (mouse)
Chr.Chromosome 3 (mouse)[2]
Chromosome 3 (mouse)
Genomic location for SUPT20H
Genomic location for SUPT20H
Band3|3 CStart54,600,228 bp[2]
End54,636,187 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • left testis

  • right testis

  • right uterine tube

  • ganglionic eminence

  • ventricular zone

  • canal of the cervix

  • right ovary

  • left ovary

  • anterior pituitary

  • body of uterus
Top expressed in
  • spermatocyte

  • spermatid

  • seminiferous tubule

  • genital tubercle

  • granulocyte

  • ascending aorta

  • aortic valve

  • internal carotid artery

  • external carotid artery

  • pituitary gland
More reference expression data
BioGPS




More reference expression data
Gene ontology
Molecular function
  • protein binding
  • transcription coregulator activity
Cellular component
  • SAGA-type complex
  • SAGA complex
  • nucleus
  • fibrillar center
Biological process
  • autophagy
  • multicellular organism development
  • gastrulation
  • regulation of nucleic acid-templated transcription
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

55578

56790

Ensembl

ENSG00000102710

ENSMUSG00000027751

UniProt

Q8NEM7

Q7TT00

RefSeq (mRNA)

NM_001014286
NM_001278480
NM_001278481
NM_001278482
NM_017569

NM_019995
NM_001358015
NM_001358017

RefSeq (protein)

NP_001014308
NP_001265409
NP_001265410
NP_001265411
NP_060039

NP_064379
NP_001344944
NP_001344946
NP_001394692
NP_001394693

NP_001394694
NP_001394695
NP_001394696
NP_001394697
NP_001394698
NP_001394699
NP_001394700
NP_001394701
NP_001394702
NP_001394703
NP_001394704
NP_001394705
NP_001394706
NP_001394707
NP_001394708
NP_001394709
NP_001394710
NP_001394711
NP_001394712
NP_001394713
NP_001394714

Location (UCSC)Chr 13: 37.01 – 37.06 MbChr 3: 54.6 – 54.64 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

SPT20 homolog is a protein that in humans is encoded by the SUPT20H gene.[5][6][7]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000102710 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027751 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Gomes I, Sharma TT, Edassery S, Fulton N, Mar BG, Westbrook CA (Jun 2002). "Novel transcription factors in human CD34 antigen-positive hematopoietic cells". Blood. 100 (1): 107–19. doi:10.1182/blood.V100.1.107. PMID 12070015.
  6. ^ Kunze D, Fuessel S, Meye A, Wirth MP, Schmidt U (May 2006). "Functional analyses of C13orf19/P38IP in prostate cell lines". Oncol Rep. 15 (6): 1599–604. doi:10.3892/or.15.6.1599. PMID 16685401.
  7. ^ "Entrez Gene: FAM48A family with sequence similarity 48, member A".

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Schmidt U, Fiedler U, Pilarsky CP, et al. (2001). "Identification of a novel gene on chromosome 13 between BRCA-2 and RB-1". Prostate. 47 (2): 91–101. doi:10.1002/pros.1051. PMID 11340631. S2CID 20381507.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522–8. Bibcode:2004Natur.428..522D. doi:10.1038/nature02379. PMC 2665288. PMID 15057823.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. Bibcode:2004PNAS..10115724W. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
  • Schmidt U, Fuessel S, Haase M, et al. (2005). "Quantification of C13orf19/P38IP mRNA expression by quantitative real-time PCR in patients with urological malignancies". Cancer Lett. 225 (2): 253–60. doi:10.1016/j.canlet.2004.10.037. PMID 15978328.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
  • Zohn IE, Li Y, Skolnik EY, et al. (2006). "p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation". Cell. 125 (5): 957–69. doi:10.1016/j.cell.2006.03.048. PMID 16751104.


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