SSFA2

Protein-coding gene in the species Homo sapiens
ITPRID2
Identifiers
AliasesITPRID2, CS-1, CS1, KRAP, SPAG13, sperm specific antigen 2, ITPR interacting domain containing 2, SSFA2
External IDsOMIM: 118990; MGI: 1917849; HomoloGene: 4912; GeneCards: ITPRID2; OMA:ITPRID2 - orthologs
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for ITPRID2
Genomic location for ITPRID2
Band2q31.3Start181,891,730 bp[1]
End181,930,738 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for ITPRID2
Genomic location for ITPRID2
Band2|2 C3Start79,465,696 bp[2]
End79,503,310 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • body of pancreas

  • tibial nerve

  • stromal cell of endometrium

  • epithelium of colon

  • sural nerve

  • skin of thigh

  • rectum

  • hair follicle

  • skin of abdomen

  • right hemisphere of cerebellum
Top expressed in
  • skin of external ear

  • pyloric antrum

  • parotid gland

  • epithelium of stomach

  • sciatic nerve

  • skin of back

  • Epithelium of choroid plexus

  • mucous cell of stomach

  • ileum

  • brown adipose tissue
More reference expression data
BioGPS
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

6744

70599

Ensembl

ENSG00000138434

ENSMUSG00000027007

UniProt

P28290

Q922B9

RefSeq (mRNA)

NM_001130445
NM_001287503
NM_001287504
NM_001287505
NM_006751

NM_080558

RefSeq (protein)

NP_001123917
NP_001274432
NP_001274433
NP_001274434
NP_006742

NP_542125

Location (UCSC)Chr 2: 181.89 – 181.93 MbChr 2: 79.47 – 79.5 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Sperm-specific antigen 2 is a protein that in humans is encoded by the SSFA2 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000138434 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027007 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Javed AA, Naz RK (March 1992). "Human cleavage signal-1 protein; cDNA cloning, transcription and immunological analysis". Gene. 112 (2): 205–11. doi:10.1016/0378-1119(92)90377-2. PMID 1555770.
  6. ^ "Entrez Gene: SSFA2 sperm specif8uuic antigen 2".

Further reading

  • Zhu X, Naz RK (October 1998). "Cloning and sequencing of cDNA encoding for a human sperm antigen involved in fertilization". Molecular Reproduction and Development. 51 (2): 176–83. doi:10.1002/(SICI)1098-2795(199810)51:2<176::AID-MRD7>3.0.CO;2-N. PMID 9740325. S2CID 22584260.
  • Nagase T, Kikuno R, Ohara O (August 2001). "Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins". DNA Research. 8 (4): 179–87. doi:10.1093/dnares/8.4.179. PMID 11572484.
  • Inokuchi J, Komiya M, Baba I, Naito S, Sasazuki T, Shirasawa S (2004). "Deregulated expression of KRAP, a novel gene encoding actin-interacting protein, in human colon cancer cells". Journal of Human Genetics. 49 (1): 46–52. doi:10.1007/s10038-003-0106-3. PMID 14673706.
  • Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (August 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
  • v
  • t
  • e