SPOCK2 |
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Identifiers |
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Aliases | SPOCK2, testican-2, sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2, SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2, SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2 |
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External IDs | OMIM: 607988; MGI: 1891351; HomoloGene: 8854; GeneCards: SPOCK2; OMA:SPOCK2 - orthologs |
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Gene location (Human) |
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![Chromosome 10 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/2/2f/Ideogram_human_chromosome_10.svg/300px-Ideogram_human_chromosome_10.svg.png) | Chr. | Chromosome 10 (human)[1] |
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| Band | 10q22.1 | Start | 72,059,034 bp[1] |
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End | 72,089,032 bp[1] |
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Gene location (Mouse) |
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![Chromosome 10 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_house_mouse_chromosome_10.svg/260px-Ideogram_house_mouse_chromosome_10.svg.png) | Chr. | Chromosome 10 (mouse)[2] |
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| Band | 10|10 B4 | Start | 59,942,041 bp[2] |
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End | 59,971,020 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - paraflocculus of cerebellum
- lateral nuclear group of thalamus
- right hemisphere of cerebellum
- Brodmann area 10
- spinal ganglia
- cerebellar vermis
- middle frontal gyrus
- dorsal motor nucleus of vagus nerve
- Pars compacta
- superior vestibular nucleus
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| Top expressed in | - habenula
- entorhinal cortex
- dorsomedial hypothalamic nucleus
- perirhinal cortex
- superior colliculus
- CA3 field
- medial dorsal nucleus
- central gray substance of midbrain
- subiculum
- dorsal tegmental nucleus
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/a/a5/PBB_GE_SPOCK2_202523_s_at_fs.png/250px-PBB_GE_SPOCK2_202523_s_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/b/b3/PBB_GE_SPOCK2_202524_s_at_fs.png/250px-PBB_GE_SPOCK2_202524_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - calcium ion binding
- glycosaminoglycan binding
- extracellular matrix binding
- metalloendopeptidase inhibitor activity
- collagen binding
| Cellular component | - extracellular region
- extracellular matrix
- extracellular space
| Biological process | - regulation of cell differentiation
- synapse assembly
- peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
- extracellular matrix organization
- signal transduction
- positive regulation of cell-substrate adhesion
- negative regulation of endopeptidase activity
- positive regulation of cell motility
- cellular response to leukemia inhibitory factor
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001134434 NM_001244950 NM_014767 |
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RefSeq (protein) | |
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NP_001127906 NP_001231879 NP_055582 |
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Location (UCSC) | Chr 10: 72.06 – 72.09 Mb | Chr 10: 59.94 – 59.97 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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