RRP9

Protein-coding gene in the species Homo sapiens
RRP9
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

4J0W, 4JXM

Identifiers
AliasesRRP9, RNU3IP2, U3-55K, ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast), ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
External IDsMGI: 2384313; HomoloGene: 3452; GeneCards: RRP9; OMA:RRP9 - orthologs
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for RRP9
Genomic location for RRP9
Band3p21.2Start51,933,429 bp[1]
End51,941,904 bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for RRP9
Genomic location for RRP9
Band9 F1|9 57.59 cMStart106,353,162 bp[2]
End106,362,623 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • gastrocnemius muscle

  • mucosa of transverse colon

  • left adrenal cortex

  • left uterine tube

  • right adrenal gland

  • right adrenal cortex

  • muscle of thigh

  • ectocervix

  • right ovary

  • granulocyte
Top expressed in
  • yolk sac

  • neural layer of retina

  • embryo

  • embryo

  • morula

  • epiblast

  • perirhinal cortex

  • ventricular zone

  • entorhinal cortex

  • muscle of thigh
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • U3 snoRNA binding
  • RNA binding
  • snoRNA binding
Cellular component
  • small-subunit processome
  • nucleolus
  • box C/D RNP complex
  • nucleoplasm
  • nucleus
Biological process
  • rRNA processing
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

9136

27966

Ensembl

ENSG00000114767

ENSMUSG00000041506

UniProt

O43818

Q91WM3

RefSeq (mRNA)

NM_004704

NM_145620

RefSeq (protein)

NP_004695

NP_663595

Location (UCSC)Chr 3: 51.93 – 51.94 MbChr 9: 106.35 – 106.36 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

U3 small nucleolar RNA-interacting protein 2 is a protein that in humans is encoded by the RRP9 gene.[5][6][7]


See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000114767 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041506 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Pluk H, Soffner J, Luhrmann R, van Venrooij WJ (Jan 1998). "cDNA Cloning and Characterization of the Human U3 Small Nucleolar Ribonucleoprotein Complex-Associated 55-Kilodalton Protein". Mol Cell Biol. 18 (1): 488–98. doi:10.1128/mcb.18.1.488. PMC 121518. PMID 9418896.
  6. ^ Verheggen C, Lafontaine DL, Samarsky D, Mouaikel J, Blanchard JM, Bordonne R, et al. (May 2002). "Mammalian and yeast U3 snoRNPs are matured in specific and related nuclear compartments". EMBO J. 21 (11): 2736–45. doi:10.1093/emboj/21.11.2736. PMC 126019. PMID 12032086.
  7. ^ "Entrez Gene: RRP9 RRP9, small subunit (SSU) processome component, homolog (yeast)".

Further reading

  • Lukowiak AA, Granneman S, Mattox SA, Speckmann WA, Jones K, Pluk H, et al. (2000). "Interaction of the U3-55k protein with U3 snoRNA is mediated by the Box B/C motif of U3 and the WD repeats of U3-55k". Nucleic Acids Res. 28 (18): 3462–71. doi:10.1093/nar/28.18.3462. PMC 110750. PMID 10982864.
  • Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
  • Granneman S, Pruijn GJ, Horstman W, Van Venrooij WJ, Luhrmann R, Watkins NJ (2003). "The hU3-55K protein requires 15.5K binding to the box B/C motif as well as flanking RNA elements for its association with the U3 small nucleolar RNA in Vitro". J. Biol. Chem. 277 (50): 48490–500. doi:10.1074/jbc.M206631200. hdl:11858/00-001M-0000-0012-F261-B. PMID 12381732.
  • Scherl A, Couté Y, Déon C, Callé A, Kindbeiter K, Sanchez JC, et al. (2003). "Functional Proteomic Analysis of Human Nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
  • Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Watkins NJ, Lemm I, Ingelfinger D, Schneider C, Hoßbach M, Urlaub H, et al. (2005). "Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex". Mol. Cell. 16 (5): 789–98. doi:10.1016/j.molcel.2004.11.012. hdl:11858/00-001M-0000-0012-EB89-8. PMID 15574333.
  • Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
  • Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788.
  • Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

External links

  • PDBe-KB provides an overview of all the structure information available in the PDB for Human U3 small nucleolar RNA-interacting protein 2 (RRP9)


  • v
  • t
  • e