RBM25

Protein-coding gene in the species Homo sapiens
RBM25
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

3V53

Identifiers
AliasesRBM25, NET52, RED120, RNPC7, S164, Snu71, fSAP94, RNA binding motif protein 25
External IDsOMIM: 612427; MGI: 1914289; HomoloGene: 136439; GeneCards: RBM25; OMA:RBM25 - orthologs
Gene location (Human)
Chromosome 14 (human)
Chr.Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for RBM25
Genomic location for RBM25
Band14q24.2Start73,058,532 bp[1]
End73,123,899 bp[1]
Gene location (Mouse)
Chromosome 12 (mouse)
Chr.Chromosome 12 (mouse)[2]
Chromosome 12 (mouse)
Genomic location for RBM25
Genomic location for RBM25
Band12|12 D1Start83,631,236 bp[2]
End83,683,123 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • tendon of biceps brachii

  • sural nerve

  • internal globus pallidus

  • visceral pleura

  • Brodmann area 23

  • pylorus

  • parietal pleura

  • cardia

  • pericardium

  • buccal mucosa cell
Top expressed in
  • genital tubercle

  • tail of embryo

  • neural layer of retina

  • zygote

  • yolk sac

  • embryo

  • ventricular zone

  • neural tube

  • embryo

  • epiblast
More reference expression data
BioGPS




More reference expression data
Gene ontology
Molecular function
  • protein binding
  • mRNA binding
  • nucleic acid binding
  • RNA binding
Cellular component
  • cytoplasm
  • nuclear speck
  • spliceosomal complex
  • nucleus
Biological process
  • regulation of apoptotic process
  • mRNA processing
  • regulation of alternative mRNA splicing, via spliceosome
  • RNA splicing
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

58517

67039

Ensembl

ENSG00000119707

ENSMUSG00000010608

UniProt

P49756

B2RY56

RefSeq (mRNA)

NM_021239

NM_027349
NM_001364415
NM_001364416

RefSeq (protein)

NP_067062

NP_081625
NP_001351344
NP_001351345

Location (UCSC)Chr 14: 73.06 – 73.12 MbChr 12: 83.63 – 83.68 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RNA-binding protein 25 is a protein that in humans is encoded by the RBM25 gene.[5][6][7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000119707 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000010608 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Sanger Centre, The; Washington University Genome Sequencing Cente, The (Jan 1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
  6. ^ Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chi H, Lin C, Li G, Holman K, Tsuda T, Mar L, Foncin JF, Bruni AC, Montesi MP, Sorbi S, Rainero I, Pinessi L, Nee L, Chumakov I, Pollen D, Brookes A, Sanseau P, Polinsky RJ, Wasco W, Da Silva HA, Haines JL, Perkicak-Vance MA, Tanzi RE, Roses AD, Fraser PE, Rommens JM, St George-Hyslop PH (Aug 1995). "Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease". Nature. 375 (6534): 754–60. Bibcode:1995Natur.375..754S. doi:10.1038/375754a0. PMID 7596406. S2CID 4308372.
  7. ^ "Entrez Gene: RBM25 RNA binding motif protein 25".

Further reading

  • Elisei R, Weightman D, Kendall-Taylor P, Vassart G, Ludgate M (1993). "Muscle autoantigens in thyroid associated ophthalmopathy: the limits of molecular genetics". J. Endocrinol. Invest. 16 (7): 533–40. doi:10.1007/bf03348900. PMID 8227983. S2CID 23857370.
  • Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Gocke CB, Yu H, Kang J (2005). "Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates". J. Biol. Chem. 280 (6): 5004–12. doi:10.1074/jbc.M411718200. PMID 15561718.
  • Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
  • Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
  • Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  • Fortes P, Longman D, McCracken S, Ip JY, Poot R, Mattaj IW, Cáceres JF, Blencowe BJ (2007). "Identification and characterization of RED120: a conserved PWI domain protein with links to splicing and 3'-end formation". FEBS Lett. 581 (16): 3087–97. doi:10.1016/j.febslet.2007.05.066. PMID 17560998. S2CID 34887603.


  • v
  • t
  • e