RASA4B

Protein-coding gene in the species Homo sapiens
RASA4B
Identifiers
AliasesRASA4B, RAS p21 protein activator 4B
External IDsMGI: 1858600; GeneCards: RASA4B; OMA:RASA4B - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for RASA4B
Genomic location for RASA4B
Band7q22.1Start102,479,976 bp[1]
End102,517,777 bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for RASA4B
Genomic location for RASA4B
Band5|5 G2Start136,083,916 bp[2]
End136,111,860 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • muscle of thigh

  • gastrocnemius muscle

  • skeletal muscle tissue

  • pituitary gland

  • right coronary artery

  • canal of the cervix

  • gastric mucosa

  • fundus

  • body of uterus

  • anterior pituitary
Top expressed in
  • primary oocyte

  • Ileal epithelium

  • zygote

  • muscle of thigh

  • secondary oocyte

  • plantaris muscle

  • neural layer of retina

  • extensor digitorum longus muscle

  • stroma of bone marrow

  • ankle joint
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • metal ion binding
  • GTPase activator activity
  • phospholipid binding
Cellular component
  • cytoplasm
  • cytosol
  • plasma membrane
  • intrinsic component of the cytoplasmic side of the plasma membrane
  • membrane
Biological process
  • regulation of GTPase activity
  • intracellular signal transduction
  • signal transduction
  • positive regulation of GTPase activity
  • negative regulation of Ras protein signal transduction
  • cellular response to calcium ion
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

100271927

54153

Ensembl

ENSG00000170667

ENSMUSG00000004952

UniProt

C9J798

Q6PFQ7

RefSeq (mRNA)

NM_001277335
NM_001367767

NM_001039103
NM_133914

RefSeq (protein)

NP_001264264
NP_001354696

NP_001034192
NP_598675

Location (UCSC)Chr 7: 102.48 – 102.52 MbChr 5: 136.08 – 136.11 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RAS p21 protein activator 4B is a protein that in humans is encoded by the RASA4B gene. [5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000170667 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000004952 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: RAS p21 protein activator 4B". Retrieved 2016-10-15.

Further reading


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