Parathion S
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Preferred IUPAC name O,O-Diethyl S-(4-nitrophenyl) phosphorothioate | |
Other names S-Phenyl parathion | |
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Properties | |
Chemical formula | C10H14NO5PS |
Molar mass | 291.26 g·mol−1 |
Appearance | Pale yellow crystalline solid |
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Lethal dose or concentration (LD, LC): | |
LD50 (median dose) | 107 μg/kg (mice, intraperitoneal)[1] 4.41 mg/kg (rats, oral)[1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
Parathion S is an organophosphate related to the organophosphate insecticide paraoxon and parathion. It's the structural isomer of parathion. Parathion S is a potent acetylcholinesterase inhibitor.[2][3]
See also
- Paraoxon
- Parathion
- Diisopropyl paraoxon
- Ro 3-0419
- Ro 3-0422
References
- ^ a b "ChemIDplus".
- ^ DIGGLE, WM; GAGE, JC (September 1951). "Cholinesterase inhibition in vitro by OO-diethyl O-p-nitrophenyl thiophosphate (parathion, E 605)". The Biochemical Journal. 49 (4): 491–4. doi:10.1042/bj0490491. PMC 1197537. PMID 14886312.
- ^ ALDRIDGE, WN; DAVISON, AN (December 1952). "The inhibition of erythrocyte cholinesterase by tri-esters of phosphoric acid. II. Diethyl p-nitrophenyl thionphosphate (E605) and analogues". The Biochemical Journal. 52 (4): 663–71. doi:10.1042/bj0520663. PMC 1198077. PMID 13018298.
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(modulators)
(modulators)
CHTTooltip Choline transporter |
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VAChTTooltip Vesicular acetylcholine transporter |
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(modulators)
Inhibitors |
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Enhancers |
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- See also
- Receptor/signaling modulators
- Muscarinic acetylcholine receptor modulators
- Nicotinic acetylcholine receptor modulators
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