PXMP4

Protein-coding gene in the species Homo sapiens
PXMP4
Identifiers
AliasesPXMP4, PMP24, peroxisomal membrane protein 4
External IDsOMIM: 616397; MGI: 1891701; HomoloGene: 5237; GeneCards: PXMP4; OMA:PXMP4 - orthologs
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for PXMP4
Genomic location for PXMP4
Band20q11.22Start33,702,758 bp[1]
End33,720,319 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for PXMP4
Genomic location for PXMP4
Band2|2 H1Start154,427,678 bp[2]
End154,445,628 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • skin of thigh

  • right adrenal cortex

  • pancreatic ductal cell

  • vulva

  • left adrenal gland

  • left adrenal cortex

  • muscle of thigh

  • parotid gland

  • mucosa of ileum

  • mucosa of transverse colon
Top expressed in
  • right kidney

  • lip

  • left lobe of liver

  • proximal tubule

  • human kidney

  • right ventricle

  • embryo

  • brown adipose tissue

  • muscle of thigh

  • skin of external ear
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • protein binding
Cellular component
  • integral component of membrane
  • peroxisomal membrane
  • peroxisome
  • membrane
Biological process
  • biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

11264

59038

Ensembl

ENSG00000101417

ENSMUSG00000000876

UniProt

Q9Y6I8

Q9JJW0

RefSeq (mRNA)

NM_183397
NM_007238

NM_021534

RefSeq (protein)

NP_009169
NP_899634

NP_067509

Location (UCSC)Chr 20: 33.7 – 33.72 MbChr 2: 154.43 – 154.45 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Peroxisomal membrane protein 4 is a protein that in humans is encoded by the PXMP4 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000101417 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000000876 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Reguenga C, Oliveira ME, Gouveia AM, Eckerskorn C, Sa-Miranda C, Azevedo JE (Jul 1999). "Identification of a 24 kDa intrinsic membrane protein from mammalian peroxisomes". Biochim Biophys Acta. 1445 (3): 337–41. doi:10.1016/s0167-4781(99)00061-5. PMID 10366717.
  6. ^ "Entrez Gene: PXMP4 peroxisomal membrane protein 4, 24kDa".

Further reading

  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Jones JM, Morrell JC, Gould SJ (2004). "PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins". J. Cell Biol. 164 (1): 57–67. doi:10.1083/jcb.200304111. PMC 2171958. PMID 14709540.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Sacksteder KA, Jones JM, South ST, et al. (2000). "PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis". J. Cell Biol. 148 (5): 931–44. doi:10.1083/jcb.148.5.931. PMC 2174547. PMID 10704444.


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