Protein-coding gene in the species Homo sapiens
MED9 |
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Identifiers |
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Aliases | MED9, MED25, mediator complex subunit 9 |
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External IDs | OMIM: 609878; MGI: 2183151; HomoloGene: 32385; GeneCards: MED9; OMA:MED9 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 17 (human)[1] |
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| Band | 17p11.2 | Start | 17,476,994 bp[1] |
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End | 17,493,221 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11|11 B1.3 | Start | 59,839,032 bp[2] |
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End | 59,853,031 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - apex of heart
- left ventricle
- right auricle
- muscle of thigh
- right frontal lobe
- gonad
- gastrocnemius muscle
- anterior cingulate cortex
- nucleus accumbens
- caudate nucleus
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| Top expressed in | - seminiferous tubule
- internal carotid artery
- yolk sac
- external carotid artery
- neural layer of retina
- lens
- somite
- muscle of thigh
- dentate gyrus of hippocampal formation granule cell
- atrium
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - transcription coregulator activity
- protein binding
| Cellular component | | Biological process | - regulation of transcription by RNA polymerase II
- regulation of transcription, DNA-templated
- transcription, DNA-templated
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 17: 17.48 – 17.49 Mb | Chr 11: 59.84 – 59.85 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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Mediator complex subunit 9 (Med9) is a protein that in humans is encoded by the MED9 gene. [5]
Function
The multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors. The protein encoded by this gene is thought to be a subunit of the Mediator complex. This gene is located within the Smith–Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008].
See also
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000141026 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000061650 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Mediator complex subunit 9". Retrieved 2018-02-06.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.