ITGA3 |
---|
|
Identifiers |
---|
Aliases | ITGA3, CD49C, GAP-B3, GAPB3, ILNEB, MSK18, VCA-2, VL3A, VLA3a, FRP-2, integrin subunit alpha 3, JEB7 |
---|
External IDs | OMIM: 605025; MGI: 96602; HomoloGene: 21129; GeneCards: ITGA3; OMA:ITGA3 - orthologs |
---|
Gene location (Human) |
---|
| Chr. | Chromosome 17 (human)[1] |
---|
| Band | 17q21.33 | Start | 50,055,968 bp[1] |
---|
End | 50,090,481 bp[1] |
---|
|
Gene location (Mouse) |
---|
| Chr. | Chromosome 11 (mouse)[2] |
---|
| Band | 11 D|11 59.01 cM | Start | 94,935,300 bp[2] |
---|
End | 94,967,627 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - metanephric glomerulus
- right coronary artery
- upper lobe of left lung
- Descending thoracic aorta
- popliteal artery
- tibial arteries
- right lung
- right lobe of thyroid gland
- ascending aorta
- left lobe of thyroid gland
|
| Top expressed in | - genital tubercle
- lumbar spinal ganglion
- decidua
- tail of embryo
- corneal stroma
- yolk sac
- crypt of lieberkuhn of small intestine
- right lung lobe
- epithelium of lens
- ileum
|
| More reference expression data |
|
---|
BioGPS | | More reference expression data |
|
---|
|
Gene ontology |
---|
Molecular function | - metal ion binding
- protein domain specific binding
- laminin binding
- collagen binding
- protease binding
- protein heterodimerization activity
- integrin binding
- fibronectin binding
- protein binding
| Cellular component | - extracellular exosome
- synapse
- integral component of membrane
- cell projection
- cell periphery
- cell junction
- growth cone
- membrane
- focal adhesion
- cell surface
- receptor complex
- synaptic membrane
- perinuclear region of cytoplasm
- excitatory synapse
- integrin complex
- basolateral plasma membrane
- filopodium membrane
- external side of plasma membrane
- integrin alpha3-beta1 complex
- plasma membrane
- growth cone filopodium
| Biological process | - positive regulation of neuron projection development
- extracellular matrix organization
- lung development
- mesodermal cell differentiation
- skin development
- maternal process involved in female pregnancy
- cell-matrix adhesion
- negative regulation of cell projection organization
- positive regulation of cell-substrate adhesion
- heart development
- dendritic spine maintenance
- positive regulation of gene expression
- nephron development
- memory
- integrin-mediated signaling pathway
- response to gonadotropin
- leukocyte migration
- renal filtration
- regulation of transforming growth factor beta receptor signaling pathway
- regulation of Wnt signaling pathway
- regulation of BMP signaling pathway
- negative regulation of Rho protein signal transduction
- exploration behavior
- positive regulation of epithelial cell migration
- neuron migration
- cell adhesion
- positive regulation of protein localization to plasma membrane
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | | |
---|
NM_013565 NM_001306071 NM_001306162 |
|
---|
RefSeq (protein) | | |
---|
NP_001293000 NP_001293091 NP_038593 |
|
---|
Location (UCSC) | Chr 17: 50.06 – 50.09 Mb | Chr 11: 94.94 – 94.97 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|