Inflammatory pseudotumor

Cell proliferation involving spindle cells

An inflammatory pseudotumor is a cell proliferation and inflammation involving spindle cells, which may occur in many parts of the body, and is of unknown case.[1]

According to the WHO classification, three lesional patterns can be observed:

  • Inflammatory myofibroblastic tumour, that can be associated with an ALK gene rearrangement
  • Plasmocytic pattern ("plasma cell granuloma"), that can be linked to IgG4-related disease
  • Fibrous and hyalinizing pattern: Pulmonary hyalinizing granuloma

References

  1. ^ Gnepp, Douglas R.; Bishop, Justin A. (5 May 2020). Gnepp's Diagnostic Surgical Pathology of the Head and Neck. Elsevier Health Sciences. p. 984. ISBN 978-0-323-54780-2.


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