George L. King

Taiwanese-born Harvard medical doctor (born 1950)

  • Joslin Diabetes Center
  • Harvard Medical School
  • NIDDK

George Liang King[a] (born 1950) is a Taiwanese-American physician-scientist and diabetologist affiliated with the Joslin Diabetes Center and Harvard Medical School. King is a researcher on how diabetes affects the Asian American population; and on diabetes-related complications. He is the inaugural Thomas J. Beatson, Jr. Chair at Harvard Medical School,[2] as well as Director of Research, Senior Vice President at the Joslin Diabetes Center, where he is also ex officio a board of trustees member.[3]

Personal life and education

King was born in 1950.[1] He moved from Taiwan to the United States with his family when he was 10 years old. He learned English from an elementary school teacher in Richmond, Virginia after living in the U.S. and was one of only two Asians in his elementary and high school classes. His father suffered from diabetes.[4]

In 1972, King earned a Bachelor of Arts degree from Johns Hopkins University,[5] and later a Doctor of Medicine degree from Duke University School of Medicine.[6] He completed residency at the University of Washington before pursuing additional training at the National Institutes of Health.[7]

Career

King has been affiliated with Joslin and Harvard since 1981.[3] He was elected to The American Society for Clinical Investigation in 1986.[8] He has published over 350 scientific papers, which have been cited nearly 100 thousand times.[9] These articles mostly correspond to topics in Internal Medicine, Endocrinology and Diabetes Mellitus. His current research aims at finding protective biochemical factors acting to prevent complications in a large, special group of medalist type 1 diabetic patients who have remained relatively healthy even after 50 or more years suffering the disease.[10][11] King also leads a national effort to improve care for diabetes in Asian Americans, who develop diabetes at low body weight.[12] King is the founder of Joslin's Asian American Diabetes Initiative, [13] which runs Asian Diabetes Clinic, a provider of exceptional patient care, and culture tailored education materials.[12] Since 2011, he Co-chair AANHPI Diabetes Coalition, a large national advocacy group aiming to improve diabetes prevention and management in Asian Americans.[14] In 2018, he was elected a Fellow of the American Association for the Advancement of Science in the biological sciences section.[15]

Research

King’s research focuses on finding the causes of diabetic complications.[16][17] He founded the Medalist Study to investigate new treatments for diabetic complications, and to understand the reasons for the high rate of diabetes in Asian Americans.[18] His laboratory studies the molecular mechanisms that cause vascular complications caused by hyperglycemia and insulin resistance.[19] He discovered that VEGF is an important causal factor in the severe form of diabetic eye disease.[20] King´s laboratory has played a pioneering role in the characterization of endogenous protective factors originating in tissues which can neutralize the toxic effect of hyperglycemia and insulin resistance.[21][22]

Awards

  • 1986 - Elected Fellow of the American Society of Clinical Investigation[23]
  • 1988 - Lilly Clinical Scholar and Visiting Professor[24]
  • 1989-1990 - Cogan Award, Association for Research in Vision and Ophthalmology[6]
  • 1996 - Alcon Research Institute Award[6]
  • 1996 - Stadie Memorial Award and Lectureship, Philadelphia Affiliate of the American Diabetes Association[7]
  • 2000 - Josiah Brown Lecture, University of California Medical School, Los Angeles, CA[25]
  • 2010 - Harry Lee Memorial Lecture; Chinese American Medical Association[26]
  • 2011 - Ramon and Victoria Lim Medical Science Lectureship; University of Iowa, Carver College of Medicine, Iowa City, Iowa[27]
  • 2011 and 2012 - Harold Amos Faculty Diversity Award; Harvard University, Harvard Medical School, Boston, MA[6]
  • 2014 - 32nd Annual Award of the Chinese Hospital Board of Trustees and Medical Staff of San Francisco[28]
  • 2015 - Edwin Bierman Lecture Award, American Diabetes Association[6]
  • 2016 - JDRF Mary Tyler Moore/S. Robert Levine Award for Clinical Research, Juvenile Diabetes Research Foundation[29]
  • 2017 - Juvenile Diabetes Foundation International "Donald Silver Excellence in Research"[30]
  • 2018 - Elected Fellow of the American Association for the Advancement of Science (AAAS)[31]
  • 2019 - Antonio Champalimaud Vision Award, Champalimaud Foundation, Champalimaud Centre for the Unknown, Lisbon, Portugal[32]
  • 2022 - Thomas J. Beatson, Jr. Chair Professor of Diabetes at Harvard Medical Scho
  • 2024 - Rongxiang Xu, MD Keynote Lecture, Diabetic Lower Extremity Symposium[33]

References

  1. ^ a b Stated in National Library of the Czech Republic authority file. NKC xx0257717. Retrieved 2024-01-14.
  2. ^ "George L. King, MD, Chief Scientific Officer at Joslin Diabetes Center Named to Newly Endowed Professorship at Harvard Medical School". Joslin Communications. Joslin Diabetes Center. March 11, 2022. Retrieved January 14, 2024.
  3. ^ a b "George King, MD". Joslin Diabetes Center. Retrieved January 14, 2024.
  4. ^ Owens, Brian (September 5, 2015). "George King: research leader at the Joslin Diabetes Center". The Lancet. 386 (9997): 947. doi:10.1016/S0140-6736(15)00110-5. ISSN 1474-547X. PMID 26369461.
  5. ^ "Curriculum Vitae". 2023. Retrieved January 14, 2024 – via MHRC Symposium.
  6. ^ a b c d e "George King, MD". Harvard Health. Harvard University. Retrieved January 14, 2024.
  7. ^ a b "George L. King, M.D." The Beatson Foundation. Retrieved January 14, 2024.
  8. ^ "George Liang King, MD". The American Society for Clinical Investigation. Retrieved January 14, 2024.
  9. ^ "George L. King". research.com.
  10. ^ "Forging new defenses against diabetic kidney disease". EurekAlert!. Retrieved April 23, 2024.
  11. ^ "Kidney Disease Therapy Could Evolve from Targeting Energy-Creating Pathway". ckdnews.com. Retrieved April 23, 2024.
  12. ^ a b "Asian American Diabetes Initiative". www.joslin.org. Retrieved June 12, 2024.
  13. ^ "Ginger Forum 2023" (PDF). Joslin Diabetes Center. 2023.
  14. ^ "Dr. George King, Chief Scientific Officer at Joslin, to Receive the JDRF Mary Tyler Moore and S. Robert Levine Excellence in Clinical Research Award for Type 1 Research". www.joslin.org. Retrieved August 22, 2024.
  15. ^ Korte, Andrea (November 27, 2018). "AAAS Honors Accomplished Scientists as 2018 Elected Fellows". American Association for the Advancement of Science.
  16. ^ He, Zhiheng; King, George L. (2004). "Microvascular complications of diabetes". Endocrinology and Metabolism Clinics of North America. 33 (1): 215–238, xi–xii. doi:10.1016/j.ecl.2003.12.003. ISSN 0889-8529. PMID 15053904.
  17. ^ King, George L.; Loeken, Mary R. (2004). "Hyperglycemia-induced oxidative stress in diabetic complications". Histochemistry and Cell Biology. 122 (4): 333–338. doi:10.1007/s00418-004-0678-9. ISSN 0948-6143. PMID 15257460.
  18. ^ Keenan, Hillary A.; Costacou, Tina; Sun, Jennifer K.; Doria, Alessandro; Cavellerano, Jerry; Coney, Joseph; Orchard, Trevor J.; Aiello, Lloyd Paul; King, George L. (2007). "Clinical factors associated with resistance to microvascular complications in diabetic patients of extreme disease duration: the 50-year medalist study". Diabetes Care. 30 (8): 1995–1997. doi:10.2337/dc06-2222. ISSN 1935-5548. PMID 17507696.
  19. ^ Kitada, Munehiro; Zhang, Zhaoyun; Mima, Akira; King, George L. (June 1, 2010). "Molecular mechanisms of diabetic vascular complications". Journal of Diabetes Investigation. 1 (3): 77–89. doi:10.1111/j.2040-1124.2010.00018.x. ISSN 2040-1116. PMC 4008020. PMID 24843412.
  20. ^ Fickweiler, Ward; Park, Hyunseok; Park, Kyoungmin; Mitzner, Margalit G.; Chokshi, Tanvi; Boumenna, Tahani; Gautier, John; Zaitsu, Yumi; Wu, I.-Hsien; Cavallerano, Jerry; Aiello, Lloyd P.; Sun, Jennifer K.; King, George L. (September 1, 2022). "Elevated Retinol Binding Protein 3 Concentrations Are Associated With Decreased Vitreous Inflammatory Cytokines, VEGF, and Progression of Diabetic Retinopathy". Diabetes Care. 45 (9): 2159–2162. doi:10.2337/dc22-0165. ISSN 1935-5548. PMC 9472483. PMID 35852358.
  21. ^ Rask-Madsen, Christian; King, George L. (January 8, 2013). "Vascular complications of diabetes: mechanisms of injury and protective factors". Cell Metabolism. 17 (1): 20–33. doi:10.1016/j.cmet.2012.11.012. ISSN 1932-7420. PMC 3546345. PMID 23312281.
  22. ^ Yu, Marc Gregory; Gordin, Daniel; Fu, Jialin; Park, Kyoungmin; Li, Qian; King, George Liang (March 4, 2024). "Protective Factors and the Pathogenesis of Complications in Diabetes". Endocrine Reviews. 45 (2): 227–252. doi:10.1210/endrev/bnad030. ISSN 1945-7189. PMC 10911956. PMID 37638875.
  23. ^ "Home". The American Society for Clinical Investigation. Retrieved August 23, 2024.
  24. ^ "Enzyme Inhibitor Drug Offers Hope For Diabetes Sufferers | News | The Harvard Crimson". www.thecrimson.com. Retrieved August 23, 2024.
  25. ^ "Josiah Brown Memorial". www.uclahealth.org. Retrieved August 23, 2024.
  26. ^ "October 9, 2010". www.camasc.org. Retrieved August 23, 2024.
  27. ^ "Ramon and Victoria Lim Medical Science Lectureship". medicine.uiowa.edu. 2024.
  28. ^ "George L. King, MD". www.camasc.org. Retrieved August 23, 2024.
  29. ^ "Breakthrough T1D Honors Type 1 Diabetes Research Champions". Breakthrough T1D. Retrieved August 23, 2024.
  30. ^ "George King, MD, Honored at the GK50 Healthcare and Life Sciences". www.joslin.org. Retrieved August 23, 2024.
  31. ^ "AAAS Honors Accomplished Scientists as 2018 Elected Fellows | American Association for the Advancement of Science (AAAS)". www.aaas.org. Retrieved August 23, 2024.
  32. ^ "Champalimaud Vision Award: Recognizing institutions combating blindness in Brazil". eurekalert.org. 2019.
  33. ^ "Agenda". Diabetic Lower Extremity Symposium. Retrieved August 23, 2024.

Notes

  1. ^ Also attested as George Liang King Jr.[1]
  • Profile – Harvard Medical School Department of Ophthalmology
  • Profile – Beth Israel Deaconess Medical Center
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