GRIK3 |
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Identifiers |
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Aliases | GRIK3, EAA5, GLR7, GLUR7, GluK3, GluR7a, glutamate ionotropic receptor kainate type subunit 3 |
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External IDs | OMIM: 138243; MGI: 95816; HomoloGene: 73901; GeneCards: GRIK3; OMA:GRIK3 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 1 (human)[1] |
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| Band | 1p34.3 | Start | 36,795,527 bp[1] |
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End | 37,034,515 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 4 (mouse)[2] |
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| Band | 4 D2.2|4 58.91 cM | Start | 125,384,493 bp[2] |
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End | 125,607,966 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - sural nerve
- spinal ganglia
- trigeminal ganglion
- prefrontal cortex
- primary visual cortex
- endothelial cell
- hypothalamus
- cingulate gyrus
- anterior cingulate cortex
- right frontal lobe
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| Top expressed in | - median eminence
- arcuate nucleus
- lateral septal nucleus
- Rostral migratory stream
- lateral hypothalamus
- ventromedial nucleus
- mammillary body
- anterior amygdaloid area
- paraventricular nucleus of hypothalamus
- primary motor cortex
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - kainate selective glutamate receptor activity
- adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
- ion channel activity
- extracellularly glutamate-gated ion channel activity
- ligand-gated ion channel activity
- ionotropic glutamate receptor activity
- G protein-coupled receptor binding
- glutamate receptor activity
- signaling receptor activity
- ligand-gated ion channel activity involved in regulation of presynaptic membrane potential
- transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
| Cellular component | - integral component of membrane
- postsynaptic membrane
- membrane
- plasma membrane
- synapse
- integral component of plasma membrane
- cell junction
- dendrite cytoplasm
- perikaryon
- dendrite
- terminal bouton
- axon
- kainate selective glutamate receptor complex
- presynaptic membrane
- glutamatergic synapse
| Biological process | - G protein-coupled glutamate receptor signaling pathway
- glutamate receptor signaling pathway
- ion transport
- ion transmembrane transport
- negative regulation of synaptic transmission, glutamatergic
- ionotropic glutamate receptor signaling pathway
- adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
- regulation of membrane potential
- excitatory postsynaptic potential
- synaptic transmission, glutamatergic
- modulation of chemical synaptic transmission
- regulation of presynaptic membrane potential
- regulation of postsynaptic membrane potential
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 1: 36.8 – 37.03 Mb | Chr 4: 125.38 – 125.61 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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