FBP1 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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1FTA, 2FHY, 2FIE, 2FIX, 2JJK, 2VT5, 2WBB, 2WBD, 2Y5K, 2Y5L, 3A29, 3KBZ, 3KC0, 3KC1, 4MJO |
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Identifiers |
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Aliases | FBP1, FBP, fructose-bisphosphatase 1 |
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External IDs | OMIM: 611570; MGI: 95492; HomoloGene: 55467; GeneCards: FBP1; OMA:FBP1 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 9 (human)[1] |
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| Band | 9q22.32 | Start | 94,603,133 bp[1] |
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End | 94,640,249 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 13 (mouse)[2] |
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| Band | 13|13 B3 | Start | 63,012,567 bp[2] |
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End | 63,036,096 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - right lobe of liver
- jejunal mucosa
- mucosa of ileum
- duodenum
- human kidney
- right lung
- upper lobe of left lung
- kidney tubule
- monocyte
- mucosa of transverse colon
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| Top expressed in | - left lobe of liver
- right kidney
- human kidney
- seminiferous tubule
- gallbladder
- spermatocyte
- spermatid
- proximal tubule
- epithelium of small intestine
- Ileal epithelium
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - protein binding
- metal ion binding
- phosphoric ester hydrolase activity
- identical protein binding
- hydrolase activity
- catalytic activity
- monosaccharide binding
- AMP binding
- phosphatase activity
- fructose 1,6-bisphosphate 1-phosphatase activity
| Cellular component | - cytoplasm
- extracellular exosome
- cytosol
- nucleus
| Biological process | - fructose metabolic process
- fructose 6-phosphate metabolic process
- cellular response to magnesium ion
- metabolism
- dephosphorylation
- regulation of gluconeogenesis
- negative regulation of cell growth
- protein homotetramerization
- negative regulation of Ras protein signal transduction
- gluconeogenesis
- sucrose biosynthetic process
- fructose 1,6-bisphosphate metabolic process
- carbohydrate metabolic process
- negative regulation of transcription by RNA polymerase II
- negative regulation of glycolytic process
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 9: 94.6 – 94.64 Mb | Chr 13: 63.01 – 63.04 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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