Epsiprantel

Chemical compound
  • QP52AA04 (WHO) QP52AA54 (WHO)
Legal statusLegal status
  • US: ℞-only
Pharmacokinetic dataBioavailabilityMinimal[1]Identifiers
  • 2-(Cyclohexylcarbonyl)-2,3,6,7,8,12b-hexahydropyrazino[2,1-a] [2]benzazepin-4(1H)-one
CAS Number
  • 98123-83-2
PubChem CID
  • 72026
ChemSpider
  • 65020
UNII
  • 0C1SPQ0FSR
ChEMBL
  • ChEMBL64979
CompTox Dashboard (EPA)
  • DTXSID3057858 Edit this at Wikidata
Chemical and physical dataFormulaC20H26N2O2Molar mass326.440 g·mol−13D model (JSmol)
  • Interactive image
  • O=C4N2C(c1c(cccc1)CCC2)CN(C(=O)C3CCCCC3)C4
InChI
  • InChI=1S/C20H26N2O2/c23-19-14-21(20(24)16-8-2-1-3-9-16)13-18-17-11-5-4-7-15(17)10-6-12-22(18)19/h4-5,7,11,16,18H,1-3,6,8-10,12-14H2
  • Key:LGUDKOQUWIHXOV-UHFFFAOYSA-N

Epsiprantel (trade name Cestex) is a veterinary drug which is used as an anthelmintic against tapeworms such as Echinococcus granulosus.[2]

Indications

It is indicated for the removal of cestodes (tapeworms) in cats (Dipylidium caninum and Taenia taeniaeformis) and dogs (Dipylidium caninum and Taenia pisiformis) 7 weeks of age and older.[1]

References

  1. ^ a b "Cestex (epsiprantel) Veterinary Tablets. Prescribing Information" (PDF). Zoetis Inc. Kalamazoo, MI 49007. Retrieved 2 October 2016.
  2. ^ Arru E, Garippa G, Manger BR (November 1990). "Efficacy of epsiprantel against Echinococcus granulosus infections in dogs". Research in Veterinary Science. 49 (3): 378–9. doi:10.1016/0034-5288(90)90080-N. PMID 2267429.
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Antiplatyhelmintic agents
Antitrematodals
(schistosomicides)
Binds tubulin
AChE inhibitor
Other/unknown
Anticestodals
(taeniacides)
Binds tubulin
Other/unknown
Antinematodal agents
(including
macrofilaricides)
Binds tubulin
Glutamate-gated chloride channel, GABA receptor
NMDA
Other/unknown
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