Epsiprantel
Chemical compound
- QP52AA04 (WHO) QP52AA54 (WHO)
- US: ℞-only
- 2-(Cyclohexylcarbonyl)-2,3,6,7,8,12b-hexahydropyrazino[2,1-a] [2]benzazepin-4(1H)-one
- 98123-83-2
- 72026
- 65020
- 0C1SPQ0FSR
- ChEMBL64979
- DTXSID3057858
- Interactive image
- O=C4N2C(c1c(cccc1)CCC2)CN(C(=O)C3CCCCC3)C4
InChI
- InChI=1S/C20H26N2O2/c23-19-14-21(20(24)16-8-2-1-3-9-16)13-18-17-11-5-4-7-15(17)10-6-12-22(18)19/h4-5,7,11,16,18H,1-3,6,8-10,12-14H2
- Key:LGUDKOQUWIHXOV-UHFFFAOYSA-N
Epsiprantel (trade name Cestex) is a veterinary drug which is used as an anthelmintic against tapeworms such as Echinococcus granulosus.[2]
Indications
It is indicated for the removal of cestodes (tapeworms) in cats (Dipylidium caninum and Taenia taeniaeformis) and dogs (Dipylidium caninum and Taenia pisiformis) 7 weeks of age and older.[1]
References
- ^ a b "Cestex (epsiprantel) Veterinary Tablets. Prescribing Information" (PDF). Zoetis Inc. Kalamazoo, MI 49007. Retrieved 2 October 2016.
- ^ Arru E, Garippa G, Manger BR (November 1990). "Efficacy of epsiprantel against Echinococcus granulosus infections in dogs". Research in Veterinary Science. 49 (3): 378–9. doi:10.1016/0034-5288(90)90080-N. PMID 2267429.
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Antitrematodals (schistosomicides) |
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Anticestodals (taeniacides) |
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(including
macrofilaricides)
Binds tubulin | |
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Glutamate-gated chloride channel, GABA receptor | |
NMDA |
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Other/unknown |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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