ERLIN2 |
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Identifiers |
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Aliases | ERLIN2, C8orf2, Erlin-2, NET32, SPFH2, SPG18, ER lipid raft associated 2 |
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External IDs | OMIM: 611605; MGI: 2387215; HomoloGene: 5193; GeneCards: ERLIN2; OMA:ERLIN2 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 8 (human)[1] |
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| Band | 8p11.23 | Start | 37,736,601 bp[1] |
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End | 37,758,422 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 8 (mouse)[2] |
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| Band | 8|8 A2 | Start | 27,513,289 bp[2] |
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End | 27,530,356 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - Epithelium of choroid plexus
- renal medulla
- Achilles tendon
- islet of Langerhans
- parotid gland
- germinal epithelium
- mucosa of paranasal sinus
- bronchial epithelial cell
- kidney tubule
- caput epididymis
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| Top expressed in | - spermatocyte
- otolith organ
- utricle
- Epithelium of choroid plexus
- right kidney
- vestibular membrane of cochlear duct
- decidua
- superior cervical ganglion
- gastrula
- proximal tubule
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - cholesterol binding
- protein binding
- protein tyrosine kinase activity
- ubiquitin protein ligase binding
| Cellular component | - integral component of membrane
- membrane raft
- membrane
- endoplasmic reticulum
- plasma membrane
- endoplasmic reticulum membrane
- cytosol
- protein-containing complex
| Biological process | - SREBP signaling pathway
- steroid metabolic process
- cholesterol metabolic process
- negative regulation of cholesterol biosynthetic process
- negative regulation of fatty acid biosynthetic process
- lipid metabolism
- ubiquitin-dependent ERAD pathway
- peptidyl-tyrosine phosphorylation
- transmembrane transport
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001003790 NM_001003791 NM_007175 NM_001362878 NM_001362880 |
| NM_153592 NM_001364476 NM_001364477 NM_001379175 NM_001379176
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NM_001379177 NM_001379178 |
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RefSeq (protein) | |
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NP_001003790 NP_001003791 NP_009106 NP_001349807 NP_001349809 |
| NP_705820 NP_001351405 NP_001351406 NP_001366104 NP_001366105
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NP_001366106 NP_001366107 NP_001391043 NP_001391044 NP_001391045 |
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Location (UCSC) | Chr 8: 37.74 – 37.76 Mb | Chr 8: 27.51 – 27.53 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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